中国科学院计算技术研究所机构知识库

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	A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16 作者:  Yang, Zhenyu;  Wang, Kai;  Zhang, Guo;  Jiang, Yuanyuan;  Zeng, Rui;  Qiao, Jingxin;  Li, Yueyue;  Deng, Xinyue;  Xia, Ziyi;  Yao, Rui;  Zeng, Xiaoxi;  Zhang, Liyun;  Zhao, Yi;  Lei, Jian;  Chen, Runsheng 收藏  |  浏览/下载：7/0  |  提交时间：2025/06/25 Structure-based bioactivity optimization  Deep-learning model  SARS-CoV-2 main protease  Molecular scaffold  Pocket-StrMod
	DPA-2: a large atomic model as a multi-task learner 期刊论文 NPJ COMPUTATIONAL MATERIALS, 2024, 卷号: 10, 期号: 1, 页码: 15 作者:  Zhang, Duo;  Liu, Xinzijian;  Zhang, Xiangyu;  Zhang, Chengqian;  Cai, Chun;  Bi, Hangrui;  Du, Yiming;  Qin, Xuejian;  Peng, Anyang;  Huang, Jiameng;  Li, Bowen;  Shan, Yifan;  Zeng, Jinzhe;  Zhang, Yuzhi;  Liu, Siyuan;  Li, Yifan;  Chang, Junhan;  Wang, Xinyan;  Zhou, Shuo;  Liu, Jianchuan;  Luo, Xiaoshan;  Wang, Zhenyu;  Jiang, Wanrun;  Wu, Jing;  Yang, Yudi;  Yang, Jiyuan;  Yang, Manyi;  Gong, Fu-Qiang;  Zhang, Linshuang;  Shi, Mengchao;  Dai, Fu-Zhi;  York, Darrin M.;  Liu, Shi;  Zhu, Tong;  Zhong, Zhicheng;  Lv, Jian;  Cheng, Jun;  Jia, Weile;  Chen, Mohan;  Ke, Guolin;  Weinan, E.;  Zhang, Linfeng;  Wang, Han 收藏  |  浏览/下载：6/0  |  提交时间：2025/06/25
	A retrospective study on the mechanism underlying quick transfer from response to resistance in a repeated recurrent chordoma patient with molecular alterations treated with Palbociclib 期刊论文 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2024, 卷号: 150, 期号: 2, 页码: 9 作者:  Zhong, Nanzhe;  Yu, Dong;  Yang, Minglei;  Lu, Xingyi;  Zhang, Qiangzu;  Wei, Wei;  Jiao, Jian;  Yang, Xinghai;  Zhu, Zhi;  Chen, Su;  Xiao, Jianru 收藏  |  浏览/下载：58/0  |  提交时间：2024/05/20 Chordoma  Palbociclib  Genomic features  Drug resistance
	TSC-VEE: A TrustZone-Based Smart Contract Virtual Execution Environment 期刊论文 IEEE TRANSACTIONS ON PARALLEL AND DISTRIBUTED SYSTEMS, 2023, 卷号: 34, 期号: 6, 页码: 1773-1788 作者:  Jian, Zhaolong;  Lu, Ye;  Qiao, Youyang;  Fang, Yaozheng;  Xie, Xueshuo;  Yang, Dayi;  Zhou, Zhiyuan;  Li, Tao 收藏  |  浏览/下载：43/0  |  提交时间：2023/12/04 Smart contracts  Blockchains  Memory management  Switches  Codes  Public key  Optimization  Blockchain  smart contract  solidity program language  TrustZone  virtual execution environment
	Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation 期刊论文 FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 23 作者:  Yang, Zhen;  Xu, Feng;  Teschendorff, Andrew E.;  Zhao, Yi;  Yao, Lei;  Li, Jian;  He, Yungang 收藏  |  浏览/下载：44/0  |  提交时间：2023/07/12 lncRNA  circRNA  DNA methylation  histone modification  transcriptional regulation  regulatory network
	Scalable algorithm simplification using quantum AND logic 期刊论文 NATURE PHYSICS, 2022, 页码: 7 作者:  Chu, Ji;  He, Xiaoyu;  Zhou, Yuxuan;  Yuan, Jiahao;  Zhang, Libo;  Guo, Qihao;  Hai, Yongju;  Han, Zhikun;  Hu, Chang-Kang;  Huang, Wenhui;  Jia, Hao;  Jiao, Dawei;  Li, Sai;  Liu, Yang;  Ni, Zhongchu;  Nie, Lifu;  Pan, Xianchuang;  Qiu, Jiawei;  Wei, Weiwei;  Nuerbolati, Wuerkaixi;  Yang, Zusheng;  Zhang, Jiajian;  Zhang, Zhida;  Zou, Wanjing;  Chen, Yuanzhen;  Deng, Xiaowei;  Deng, Xiuhao;  Hu, Ling;  Li, Jian;  Liu, Song;  Lu, Yao;  Niu, Jingjing;  Tan, Dian;  Xu, Yuan;  Yan, Tongxing;  Zhong, Youpeng;  Yan, Fei;  Sun, Xiaoming;  Yu, Dapeng 收藏  |  浏览/下载：43/0  |  提交时间：2023/07/12
	BgNet: Classification of benign and malignant tumors with MRI multi-plane attention learning 期刊论文 FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 12 作者:  Liu, Hong;  Jiao, Meng-Lei;  Xing, Xiao-Ying;  Ou-Yang, Han-Qiang;  Yuan, Yuan;  Liu, Jian-Fang;  Li, Yuan;  Wang, Chun-Jie;  Lang, Ning;  Qian, Yue-Liang;  Jiang, Liang;  Yuan, Hui-Shu;  Wang, Xiang-Dong 收藏  |  浏览/下载：49/0  |  提交时间：2023/07/12 tumor classification  deep learning  multi-plane fusion  benign  malignant
	AbdomenCT-1K: Is Abdominal Organ Segmentation a Solved Problem? 期刊论文 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2022, 卷号: 44, 期号: 10, 页码: 6695-6714 作者:  Ma, Jun;  Zhang, Yao;  Gu, Song;  Zhu, Cheng;  Ge, Cheng;  Zhang, Yichi;  An, Xingle;  Wang, Congcong;  Wang, Qiyuan;  Liu, Xin;  Cao, Shucheng;  Zhang, Qi;  Liu, Shangqing;  Wang, Yunpeng;  Li, Yuhui;  He, Jian;  Yang, Xiaoping 收藏  |  浏览/下载：60/0  |  提交时间：2022/12/07 Benchmark testing  Liver  Image segmentation  Biological systems  Pancreas  Computed tomography  Kidney  Multi-organ segmentation  generalization  semi-supervised learning  weakly supervised learning  continual learning
	VoxSeP: semi-positive voxels assist self-supervised 3D medical segmentation 期刊论文 MULTIMEDIA SYSTEMS, 2022, 页码: 16 作者:  Yang, Zijie;  Xie, Lingxi;  Zhou, Wei;  Huo, Xinyue;  Wei, Longhui;  Lu, Jian;  Tian, Qi;  Tang, Sheng 收藏  |  浏览/下载：38/0  |  提交时间：2022/12/07 3D medical image segmentation  Contrastive learning  Self-supervised learning  Unsupervised learning
	Off-Line Evaluation of Indoor Positioning Systems in Different Scenarios: The Experiences From IPIN 2020 Competition 期刊论文 IEEE SENSORS JOURNAL, 2022, 卷号: 22, 期号: 6, 页码: 5011-5054 作者:  Potorti, Francesco;  Torres-Sospedra, Joaquin;  Quezada-Gaibor, Darwin;  Jimenez, Antonio Ramon;  Seco, Fernando;  Perez-Navarro, Antoni;  Ortiz, Miguel;  Zhu, Ni;  Renaudin, Valerie;  Ichikari, Ryosuke;  Shimomura, Ryo;  Ohta, Nozomu;  Nagae, Satsuki;  Kurata, Takeshi;  Wei, Dongyan;  Ji, Xinchun;  Zhang, Wenchao;  Kram, Sebastian;  Stahlke, Maximilian;  Mutschler, Christopher;  Crivello, Antonino;  Barsocchi, Paolo;  Girolami, Michele;  Palumbo, Filippo;  Chen, Ruizhi;  Wu, Yuan;  Li, Wei;  Yu, Yue;  Xu, Shihao;  Huang, Lixiong;  Liu, Tao;  Kuang, Jian;  Niu, Xiaoji;  Yoshida, Takuto;  Nagata, Yoshiteru;  Fukushima, Yuto;  Fukatani, Nobuya;  Hayashida, Nozomi;  Asai, Yusuke;  Urano, Kenta;  Ge, Wenfei;  Lee, Nien-Ting;  Fang, Shih-Hau;  Jie, You-Cheng;  Young, Shawn-Rong;  Chien, Ying-Ren;  Yu, Chih-Chieh;  Ma, Chengqi;  Wu, Bang;  Zhang, Wei;  Wang, Yankun;  Fan, Yonglei;  Poslad, Stefan;  Selviah, David R.;  Wang, Weixi;  Yuan, Hong;  Yonamoto, Yoshitomo;  Yamaguchi, Masahiro;  Kaichi, Tomoya;  Zhou, Baoding;  Liu, Xu;  Gu, Zhining;  Yang, Chengjing;  Wu, Zhiqian;  Xie, Doudou;  Huang, Can;  Zheng, Lingxiang;  Peng, Ao;  Jin, Ge;  Wang, Qu;  Luo, Haiyong;  Xiong, Hao;  Bao, Linfeng;  Zhang, Pushuo;  Zhao, Fang;  Yu, Chia-An;  Hung, Chun-Hao;  Antsfeld, Leonid;  Chidlovskii, Boris;  Jiang, Haitao;  Xia, Ming;  Yan, Dayu;  Li, Yuhang;  Dong, Yitong;  Silva, Ivo;  Pendao, Cristiano;  Meneses, Filipe;  Nicolau, Maria Joao;  Costa, Antonio;  Moreira, Adriano;  De Cock, Cedric;  Plets, David;  Opiela, Miroslav;  Dzama, Jakub;  Zhang, Liqiang;  Li, Hu;  Chen, Boxuan;  Liu, Yu;  Yean, Seanglidet;  Lim, Bo Zhi;  Teo, Wei Jie;  Lee, Bu Sung;  Oh, Hong Lye 收藏  |  浏览/下载：54/0  |  提交时间：2022/12/07 Sensor phenomena and characterization  Indoor navigation  Testing  Standards  Satellite broadcasting  Recurrent neural networks  Received signal strength indicator  Indoor positioning and navigation  evaluation  smartphone-based positioning  foot-mounted IMU  positioning in industrial scenarios and factories  vehicle-positioning