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Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 19
作者:  Qi, Xiaoning;  Zhao, Lianhe;  Tian, Chenyu;  Li, Yueyue;  Chen, Zhen-Lin;  Huo, Peipei;  Chen, Runsheng;  Liu, Xiaodong;  Wan, Baoping;  Yang, Shengyong;  Zhao, Yi
收藏  |  浏览/下载:2/0  |  提交时间:2024/12/06
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model 期刊论文
CELL RESEARCH, 2024, 页码: 16
作者:  Yang, Xiaodong;  Liu, Guole;  Feng, Guihai;  Bu, Dechao;  Wang, Pengfei;  Jiang, Jie;  Chen, Shubai;  Yang, Qinmeng;  Miao, Hefan;  Zhang, Yiyang;  Man, Zhenpeng;  Liang, Zhongming;  Wang, Zichen;  Li, Yaning;  Li, Zheng;  Liu, Yana;  Tian, Yao;  Liu, Wenhao;  Li, Cong;  Li, Ao;  Dong, Jingxi;  Hu, Zhilong;  Fang, Chen;  Cui, Lina;  Deng, Zixu;  Jiang, Haiping;  Cui, Wentao;  Zhang, Jiahao;  Yang, Zhaohui;  Li, Handong;  He, Xingjian;  Zhong, Liqun;  Zhou, Jiaheng;  Wang, Zijian;  Long, Qingqing;  Xu, Ping;  Wang, Hongmei;  Meng, Zhen;  Wang, Xuezhi;  Wang, Yangang;  Wang, Yong;  Zhang, Shihua;  Guo, Jingtao;  Zhao, Yi;  Zhou, Yuanchun;  Li, Fei;  Liu, Jing;  Chen, Yiqiang;  Yang, Ge;  Li, Xin
收藏  |  浏览/下载:4/0  |  提交时间:2024/12/06
dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms (vol 20, pg 446, 2022) 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 1, 页码: 1
作者:  Xu, Feng;  Wang, Yifan;  Ling, Yunchao;  Zhou, Chenfen;  Wang, Haizhou;  Teschendorff, Andrew E.;  Zhao, Yi;  Zhao, Haitao;  He, Yungang;  Zhang, Guoqing;  Yang, Zhen
收藏  |  浏览/下载:6/0  |  提交时间:2024/12/06
JCcirc: circRNA full-length sequence assembly through integrated junction contigs 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2023, 卷号: 24, 期号: 6, 页码: 11
作者:  Zhang, Jingjing;  Zhang, Huiling;  Ju, Zhen;  Peng, Yin;  Pan, Yi;  Xi, Wenhui;  Wei, Yanjie
收藏  |  浏览/下载:12/0  |  提交时间:2024/05/20
circRNA  full-length sequence  transcriptome  junction contig  
Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 23
作者:  Yang, Zhen;  Xu, Feng;  Teschendorff, Andrew E.;  Zhao, Yi;  Yao, Lei;  Li, Jian;  He, Yungang
收藏  |  浏览/下载:22/0  |  提交时间:2023/07/12
lncRNA  circRNA  DNA methylation  histone modification  transcriptional regulation  regulatory network  
dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2022, 卷号: 20, 期号: 3, 页码: 446-454
作者:  Xu, Feng;  Wang, Yifan;  Ling, Yunchao;  Zhou, Chenfen;  Wang, Haizhou;  Teschendorff, Andrew E.;  Zhao, Yi;  Zhao, Haitao;  He, Yungang;  Zhang, Guoqing;  Yang, Zhen
收藏  |  浏览/下载:24/0  |  提交时间:2023/07/12
MicroRNA  Cancer  Differential expression  Model organism  Database  
An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2 期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 13
作者:  Zhang, Haiping;  Li, Junxin;  Saravanan, Konda Mani;  Wu, Hao;  Wang, Zhichao;  Wu, Du;  Wei, Yanjie;  Lu, Zhen;  Chen, Youhai H.;  Wan, Xiaochun;  Pan, Yi
收藏  |  浏览/下载:38/0  |  提交时间:2022/06/21
TIPE2  UM-164  virtual screening  deep learning  molecular dynamics simulation  
Parametric local multiview hamming distance metric learning 期刊论文
PATTERN RECOGNITION, 2018, 卷号: 75, 页码: 250-262
作者:  Zhai, Deming;  Liu, Xianming;  Chang, Hong;  Zhen, Yi;  Chen, Xilin;  Guo, Maozu;  Gao, Wen
收藏  |  浏览/下载:78/0  |  提交时间:2019/12/10
Metric learning  Hamming distance  Hash function learning  
基于可穿戴设备的跌倒检测算法综述 期刊论文
浙江大学学报(工学版), 2018, 卷号: 52.0, 期号: 009, 页码: 1717
作者:  忽丽莎;  王素贞;  陈益强;  高晨龙;  胡春雨;  蒋鑫龙;  陈振宇;  高兴宇
收藏  |  浏览/下载:15/0  |  提交时间:2023/12/04
可穿戴设备  跌倒检测  健康监护  机器学习  
基于目标均衡度量的核增量学习跌倒检测方法 期刊论文
计算机应用, 2018, 卷号: 38.0, 期号: 004, 页码: 928
作者:  忽丽莎;  王素贞;  陈益强;  胡春雨;  蒋鑫龙;  陈振宇;  高兴宇
收藏  |  浏览/下载:13/0  |  提交时间:2023/12/04
增量学习  神经网络  核函数  跌倒检测  可穿戴设备