中国科学院计算技术研究所机构知识库

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	A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16 作者:  Yang, Zhenyu;  Wang, Kai;  Zhang, Guo;  Jiang, Yuanyuan;  Zeng, Rui;  Qiao, Jingxin;  Li, Yueyue;  Deng, Xinyue;  Xia, Ziyi;  Yao, Rui;  Zeng, Xiaoxi;  Zhang, Liyun;  Zhao, Yi;  Lei, Jian;  Chen, Runsheng 收藏  |  浏览/下载：7/0  |  提交时间：2025/06/25 Structure-based bioactivity optimization  Deep-learning model  SARS-CoV-2 main protease  Molecular scaffold  Pocket-StrMod
	Auto-focus scanning surface plasmon resonance microscopy 期刊论文 OPTICS EXPRESS, 2025, 卷号: 33, 期号: 7, 页码: 16551-16561 作者:  Sun, Sheng;  Liu, Pengbin;  Hu, Jingfang;  Zhang, Lingqian;  Li, Mingxiao;  Lu, Xinchao;  Zhao, Yang;  Zhi, Tian;  Huang, Chengjun 收藏  |  浏览/下载：0/0  |  提交时间：2025/06/25
	Trident: The Acceleration Architecture for High-Performance Private Set Intersection 期刊论文 IEEE TRANSACTIONS ON COMPUTERS, 2025, 卷号: 74, 期号: 4, 页码: 1152-1167 作者:  Zhang, Jinkai;  Yang, Yinghao;  Zhou, Zhe;  Hu, Zhicheng;  Zhao, Xin;  Chang, Liang;  Lu, Hang;  Li, Xiaowei 收藏  |  浏览/下载：4/0  |  提交时间：2025/06/25 Protocols  Receivers  Cryptography  Hardware  Central Processing Unit  Random access memory  Data privacy  Polynomials  Field programmable gate arrays  Computer architecture  Private set intersection (PSI)  fully homomorphic encryption (FHE)  FPGA accelerator  privacy computing
	Intelligent imaging technology applications in multidisciplinary hospitals 期刊论文 CHINESE MEDICAL JOURNAL, 2024, 卷号: 137, 期号: 24, 页码: 3083-3092 作者:  Fan, Ke;  Yang, Lei;  Ren, Fei;  Zhang, Xueyuan;  Liu, Bo;  Zhao, Ze;  Gu, Jianwen 收藏  |  浏览/下载：2/0  |  提交时间：2025/06/25 Intelligent imaging technology  Artificial intelligence  Medical imaging  Machine learning  Deep learning  Cardiology  Neurology  Oncology
	DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures 期刊论文 COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625 作者:  Qiao, Yixuan;  Yang, Rui;  Liu, Yang;  Chen, Jiaxin;  Zhao, Lianhe;  Huo, Peipei;  Wang, Zhihao;  Bu, Dechao;  Wu, Yang;  Zhao, Yi 收藏  |  浏览/下载：37/0  |  提交时间：2024/05/20 Information fusion  Deep learning  RNA -binding proteins  In vivo RNA structures  Motifs
	HERB 2.0: an updated database integrating clinical and experimental evidence for traditional Chinese medicine 期刊论文 NUCLEIC ACIDS RESEARCH, 2024, 页码: 11 作者:  Gao, Kai;  Liu, Liu;  Lei, Shuangshuang;  Li, Zhinong;  Huo, Peipei;  Wang, Zhihao;  Dong, Lei;  Deng, Wenxin;  Bu, Dechao;  Zeng, Xiaoxi;  Li, Chun;  Zhao, Yi;  Zhang, Wei;  Wang, Wei;  Wu, Yang 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25
	Cost-Effective DNA Storage System with DNA Movable Type 期刊论文 ADVANCED SCIENCE, 2024, 页码: 15 作者:  Wang, Chenyang;  Wei, Di;  Wei, Zheng;  Yang, Dongxin;  Xing, Jing;  Wang, Yunze;  Wang, Xiaotong;  Wang, Pei;  Ma, Guannan;  Zhang, Xinru;  Li, Haolan;  Tang, Chuan;  Hou, Pengfei;  Wang, Jie;  Gao, Renjun;  Xie, Guiqiu;  Li, Cuidan;  Ju, Yingjiao;  Wang, Peihan;  Yue, Liya;  Zhao, Yongliang;  Sheng, Yongjie;  Xiao, Jingfa;  Niu, Haitao;  Xu, Sihong;  Yang, Huaiyi;  Liu, Di;  Duan, Bo;  Bu, Dongbo;  Tan, Guangming;  Chen, Fei 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25 DNA data storage  DNA movable type  DNA-based storage
	Recent advances in fish cutting: From cutting schemes to automatic technologies and internet of things innovations 期刊论文 COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2024, 卷号: 23, 期号: 6, 页码: 24 作者:  Li, Qing;  Ma, Huawei;  Min, Weiqing;  Wang, Yang;  Zhao, Ran;  Zhou, Yongjie;  Tan, Yuqing;  Luo, Yongkang;  Hong, Hui 收藏  |  浏览/下载：2/0  |  提交时间：2025/06/25 AI  automation  digital monitoring system  fish cutting  IoT
	Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery 期刊论文 NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 19 作者:  Qi, Xiaoning;  Zhao, Lianhe;  Tian, Chenyu;  Li, Yueyue;  Chen, Zhen-Lin;  Huo, Peipei;  Chen, Runsheng;  Liu, Xiaodong;  Wan, Baoping;  Yang, Shengyong;  Zhao, Yi 收藏  |  浏览/下载：18/0  |  提交时间：2024/12/06
	GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model 期刊论文 CELL RESEARCH, 2024, 页码: 16 作者:  Yang, Xiaodong;  Liu, Guole;  Feng, Guihai;  Bu, Dechao;  Wang, Pengfei;  Jiang, Jie;  Chen, Shubai;  Yang, Qinmeng;  Miao, Hefan;  Zhang, Yiyang;  Man, Zhenpeng;  Liang, Zhongming;  Wang, Zichen;  Li, Yaning;  Li, Zheng;  Liu, Yana;  Tian, Yao;  Liu, Wenhao;  Li, Cong;  Li, Ao;  Dong, Jingxi;  Hu, Zhilong;  Fang, Chen;  Cui, Lina;  Deng, Zixu;  Jiang, Haiping;  Cui, Wentao;  Zhang, Jiahao;  Yang, Zhaohui;  Li, Handong;  He, Xingjian;  Zhong, Liqun;  Zhou, Jiaheng;  Wang, Zijian;  Long, Qingqing;  Xu, Ping;  Wang, Hongmei;  Meng, Zhen;  Wang, Xuezhi;  Wang, Yangang;  Wang, Yong;  Zhang, Shihua;  Guo, Jingtao;  Zhao, Yi;  Zhou, Yuanchun;  Li, Fei;  Liu, Jing;  Chen, Yiqiang;  Yang, Ge;  Li, Xin 收藏  |  浏览/下载：18/0  |  提交时间：2024/12/06