中国科学院计算技术研究所机构知识库

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	A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16 作者:  Yang, Zhenyu;  Wang, Kai;  Zhang, Guo;  Jiang, Yuanyuan;  Zeng, Rui;  Qiao, Jingxin;  Li, Yueyue;  Deng, Xinyue;  Xia, Ziyi;  Yao, Rui;  Zeng, Xiaoxi;  Zhang, Liyun;  Zhao, Yi;  Lei, Jian;  Chen, Runsheng 收藏  |  浏览/下载：7/0  |  提交时间：2025/06/25 Structure-based bioactivity optimization  Deep-learning model  SARS-CoV-2 main protease  Molecular scaffold  Pocket-StrMod
	Resistive memory-based zero-shot liquid state machine for multimodal event data learning 期刊论文 NATURE COMPUTATIONAL SCIENCE, 2025, 卷号: 5, 期号: 1, 页码: 37-47 作者:  Lin, Ning;  Wang, Shaocong;  Li, Yi;  Wang, Bo;  Shi, Shuhui;  He, Yangu;  Zhang, Woyu;  Yu, Yifei;  Zhang, Yue;  Zhang, Xinyuan;  Wong, Kwunhang;  Wang, Songqi;  Chen, Xiaoming;  Jiang, Hao;  Zhang, Xumeng;  Lin, Peng;  Xu, Xiaoxin;  Qi, Xiaojuan;  Wang, Zhongrui;  Shang, Dashan;  Liu, Qi;  Liu, Ming 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25
	Adaptive Dual-Axis Style-Based Recalibration Network With Class-Wise Statistics Loss for Imbalanced Medical Image Classification 期刊论文 IEEE TRANSACTIONS ON IMAGE PROCESSING, 2025, 卷号: 34, 页码: 2081-2096 作者:  Zhang, Xiaoqing;  Xiao, Zunjie;  Ma, Jingzhe;  Wu, Xiao;  Zhao, Jilu;  Zhang, Shuai;  Li, Runzhi;  Pan, Yi;  Liu, Jiang 收藏  |  浏览/下载：2/0  |  提交时间：2025/06/25 Imbalanced medical image classification  dual-axis style-based recalibration  imbalanced learning  class-wise statistics loss  confidence calibration  Imbalanced medical image classification  dual-axis style-based recalibration  imbalanced learning  class-wise statistics loss  confidence calibration
	Performance Modeling of Relay Chain 期刊论文 IEEE-ACM TRANSACTIONS ON NETWORKING, 2024, 页码: 16 作者:  Li, Bo;  Duan, Tiantian;  Zhao, Qinglin;  Guo, Yi;  Song, Zhaoxiong;  Zhang, Hanwen;  Li, Zhongcheng;  Sun, Yi 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25 Relays  Blockchains  Fabrics  Bitcoin  Analytical models  Delays  Protocols  Packaging  Performance analysis  Mathematical models  Blockchain  performance analysis  relay chain  cross-chain transactions  batch arrival and bulk service  modeling
	Enzyme Repertoires and Genomic Insights into Lycium barbarum Pectin Polysaccharide Biosynthesis 期刊论文 GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 6, 页码: 15 作者:  Yue, Haiyan;  Tang, Yiheng;  Li, Aixuan;  Zhang, Lili;  Niu, Yiwei;  Zhang, Yiming;  Wang, Hao;  Luo, Jianjun;  Zhao, Yi;  He, Shunmin;  Chen, Chang;  Chen, Runsheng 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25 Lycium barbarum  Lycium barbarum pectin polysaccharide  Phylogenetic expansion  lncRNA  Rhamnogalacturonan I rhamnosyltransferase
	HERB 2.0: an updated database integrating clinical and experimental evidence for traditional Chinese medicine 期刊论文 NUCLEIC ACIDS RESEARCH, 2024, 页码: 11 作者:  Gao, Kai;  Liu, Liu;  Lei, Shuangshuang;  Li, Zhinong;  Huo, Peipei;  Wang, Zhihao;  Dong, Lei;  Deng, Wenxin;  Bu, Dechao;  Zeng, Xiaoxi;  Li, Chun;  Zhao, Yi;  Zhang, Wei;  Wang, Wei;  Wu, Yang 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25
	GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model 期刊论文 CELL RESEARCH, 2024, 页码: 16 作者:  Yang, Xiaodong;  Liu, Guole;  Feng, Guihai;  Bu, Dechao;  Wang, Pengfei;  Jiang, Jie;  Chen, Shubai;  Yang, Qinmeng;  Miao, Hefan;  Zhang, Yiyang;  Man, Zhenpeng;  Liang, Zhongming;  Wang, Zichen;  Li, Yaning;  Li, Zheng;  Liu, Yana;  Tian, Yao;  Liu, Wenhao;  Li, Cong;  Li, Ao;  Dong, Jingxi;  Hu, Zhilong;  Fang, Chen;  Cui, Lina;  Deng, Zixu;  Jiang, Haiping;  Cui, Wentao;  Zhang, Jiahao;  Yang, Zhaohui;  Li, Handong;  He, Xingjian;  Zhong, Liqun;  Zhou, Jiaheng;  Wang, Zijian;  Long, Qingqing;  Xu, Ping;  Wang, Hongmei;  Meng, Zhen;  Wang, Xuezhi;  Wang, Yangang;  Wang, Yong;  Zhang, Shihua;  Guo, Jingtao;  Zhao, Yi;  Zhou, Yuanchun;  Li, Fei;  Liu, Jing;  Chen, Yiqiang;  Yang, Ge;  Li, Xin 收藏  |  浏览/下载：19/0  |  提交时间：2024/12/06
	FedBone: Towards Large-Scale Federated Multi-Task Learning 期刊论文 JOURNAL OF COMPUTER SCIENCE AND TECHNOLOGY, 2024, 卷号: 39, 期号: 5, 页码: 1040-1057 作者:  Chen, Yi-Qiang;  Zhang, Teng;  Jiang, Xin-Long;  Chen, Qian;  Gao, Chen-Long;  Huang, Wu-Liang 收藏  |  浏览/下载：6/0  |  提交时间：2025/06/25 federated learning  multi-task learning  split learning  heterogeneous task
	dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms (vol 20, pg 446, 2022) 期刊论文 GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 1, 页码: 1 作者:  Xu, Feng;  Wang, Yifan;  Ling, Yunchao;  Zhou, Chenfen;  Wang, Haizhou;  Teschendorff, Andrew E.;  Zhao, Yi;  Zhao, Haitao;  He, Yungang;  Zhang, Guoqing;  Yang, Zhen 收藏  |  浏览/下载：48/0  |  提交时间：2024/12/06
	Research on Aspect-Level Sentiment Analysis Based on Adversarial Training and Dependency Parsing 期刊论文 ELECTRONICS, 2024, 卷号: 13, 期号: 10, 页码: 16 作者:  Xu, Erfeng;  Zhu, Junwu;  Zhang, Luchen;  Wang, Yi;  Lin, Wei 收藏  |  浏览/下载：16/0  |  提交时间：2024/12/06 multi head attention mechanism  dependency syntactic relationships  adjacency matrix  adversarial training