中国科学院计算技术研究所机构知识库

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	A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16 作者:  Yang, Zhenyu;  Wang, Kai;  Zhang, Guo;  Jiang, Yuanyuan;  Zeng, Rui;  Qiao, Jingxin;  Li, Yueyue;  Deng, Xinyue;  Xia, Ziyi;  Yao, Rui;  Zeng, Xiaoxi;  Zhang, Liyun;  Zhao, Yi;  Lei, Jian;  Chen, Runsheng 收藏  |  浏览/下载：7/0  |  提交时间：2025/06/25 Structure-based bioactivity optimization  Deep-learning model  SARS-CoV-2 main protease  Molecular scaffold  Pocket-StrMod
	DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures 期刊论文 COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625 作者:  Qiao, Yixuan;  Yang, Rui;  Liu, Yang;  Chen, Jiaxin;  Zhao, Lianhe;  Huo, Peipei;  Wang, Zhihao;  Bu, Dechao;  Wu, Yang;  Zhao, Yi 收藏  |  浏览/下载：37/0  |  提交时间：2024/05/20 Information fusion  Deep learning  RNA -binding proteins  In vivo RNA structures  Motifs
	HERB 2.0: an updated database integrating clinical and experimental evidence for traditional Chinese medicine 期刊论文 NUCLEIC ACIDS RESEARCH, 2024, 页码: 11 作者:  Gao, Kai;  Liu, Liu;  Lei, Shuangshuang;  Li, Zhinong;  Huo, Peipei;  Wang, Zhihao;  Dong, Lei;  Deng, Wenxin;  Bu, Dechao;  Zeng, Xiaoxi;  Li, Chun;  Zhao, Yi;  Zhang, Wei;  Wang, Wei;  Wu, Yang 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25
	Cost-Effective DNA Storage System with DNA Movable Type 期刊论文 ADVANCED SCIENCE, 2024, 页码: 15 作者:  Wang, Chenyang;  Wei, Di;  Wei, Zheng;  Yang, Dongxin;  Xing, Jing;  Wang, Yunze;  Wang, Xiaotong;  Wang, Pei;  Ma, Guannan;  Zhang, Xinru;  Li, Haolan;  Tang, Chuan;  Hou, Pengfei;  Wang, Jie;  Gao, Renjun;  Xie, Guiqiu;  Li, Cuidan;  Ju, Yingjiao;  Wang, Peihan;  Yue, Liya;  Zhao, Yongliang;  Sheng, Yongjie;  Xiao, Jingfa;  Niu, Haitao;  Xu, Sihong;  Yang, Huaiyi;  Liu, Di;  Duan, Bo;  Bu, Dongbo;  Tan, Guangming;  Chen, Fei 收藏  |  浏览/下载：5/0  |  提交时间：2025/06/25 DNA data storage  DNA movable type  DNA-based storage
	Recent advances in fish cutting: From cutting schemes to automatic technologies and internet of things innovations 期刊论文 COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2024, 卷号: 23, 期号: 6, 页码: 24 作者:  Li, Qing;  Ma, Huawei;  Min, Weiqing;  Wang, Yang;  Zhao, Ran;  Zhou, Yongjie;  Tan, Yuqing;  Luo, Yongkang;  Hong, Hui 收藏  |  浏览/下载：2/0  |  提交时间：2025/06/25 AI  automation  digital monitoring system  fish cutting  IoT
	GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model 期刊论文 CELL RESEARCH, 2024, 页码: 16 作者:  Yang, Xiaodong;  Liu, Guole;  Feng, Guihai;  Bu, Dechao;  Wang, Pengfei;  Jiang, Jie;  Chen, Shubai;  Yang, Qinmeng;  Miao, Hefan;  Zhang, Yiyang;  Man, Zhenpeng;  Liang, Zhongming;  Wang, Zichen;  Li, Yaning;  Li, Zheng;  Liu, Yana;  Tian, Yao;  Liu, Wenhao;  Li, Cong;  Li, Ao;  Dong, Jingxi;  Hu, Zhilong;  Fang, Chen;  Cui, Lina;  Deng, Zixu;  Jiang, Haiping;  Cui, Wentao;  Zhang, Jiahao;  Yang, Zhaohui;  Li, Handong;  He, Xingjian;  Zhong, Liqun;  Zhou, Jiaheng;  Wang, Zijian;  Long, Qingqing;  Xu, Ping;  Wang, Hongmei;  Meng, Zhen;  Wang, Xuezhi;  Wang, Yangang;  Wang, Yong;  Zhang, Shihua;  Guo, Jingtao;  Zhao, Yi;  Zhou, Yuanchun;  Li, Fei;  Liu, Jing;  Chen, Yiqiang;  Yang, Ge;  Li, Xin 收藏  |  浏览/下载：19/0  |  提交时间：2024/12/06
	dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms (vol 20, pg 446, 2022) 期刊论文 GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 1, 页码: 1 作者:  Xu, Feng;  Wang, Yifan;  Ling, Yunchao;  Zhou, Chenfen;  Wang, Haizhou;  Teschendorff, Andrew E.;  Zhao, Yi;  Zhao, Haitao;  He, Yungang;  Zhang, Guoqing;  Yang, Zhen 收藏  |  浏览/下载：48/0  |  提交时间：2024/12/06
	Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration 期刊论文 ISCIENCE, 2024, 卷号: 27, 期号: 4, 页码: 22 作者:  Li, Hongyi;  Li, Bei;  Luo, Wenqi;  Qi, Xi;  Hao, You;  Yang, Chaozhi;  Li, Wenqing;  Li, Jiazheng;  Hua, Zhen;  Guo, Tan;  Zheng, Zhijian;  Yu, Xue;  Liu, Lei;  Zhao, Jianping;  Li, Tiantian;  Huang, Dahai;  Hu, Jun;  Li, Zongmin;  Wang, Fang;  Li, Hua;  Ma, Chao;  Ji, Fusui 收藏  |  浏览/下载：29/0  |  提交时间：2024/12/06
	Explainability for Large Language Models: A Survey 期刊论文 ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY, 2024, 卷号: 15, 期号: 2, 页码: 38 作者:  Zhao, Haiyan;  Chen, Hanjie;  Yang, Fan;  Liu, Ninghao;  Deng, Huiqi;  Cai, Hengyi;  Wang, Shuaiqiang;  Yin, Dawei;  Du, Mengnan 收藏  |  浏览/下载：13/0  |  提交时间：2024/12/06 Explainability  interpretability  large language models
	Improving the Scalability of Distributed Network Emulations: An Algorithmic Perspective 期刊论文 IEEE TRANSACTIONS ON NETWORK AND SERVICE MANAGEMENT, 2023, 卷号: 20, 期号: 4, 页码: 4325-4339 作者:  Zhao, Huaiyi;  Zhang, Xinyi;  Wang, Yang;  Diao, Zulong;  Li, Yanbiao;  Xie, Gaogang 收藏  |  浏览/下载：23/0  |  提交时间：2024/05/20 Distributed network emulations  service assurance  performance evaluations  large-scale experimental platforms  optimization theories  multilevel algorithms