中国科学院计算技术研究所机构知识库

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	Chinese Immune Multi-Omics Atlas 期刊论文 SCIENCE, 2026, 卷号: 391, 期号: 6781, 页码: 25 作者:  Yin, Jianhua;  Zheng, Yuhui;  Huang, Zhuoli;  Zhou, Wenwen;  Yuan, Yue;  Cai, Pengfei;  Bai, Yong;  Yang, Shichen;  Gao, Yue;  Duan, Shanshan;  Wang, Yang;  Xu, Zekai;  Zhang, Wenxi;  Zhang, Xinyu;  Wei, Yilin;  Huang, Yaling;  Liu, Ying;  Wang, Weikai;  Yang, Tao;  Zhang, Zhongjin;  Chen, Xiaoya;  Zhang, Xiru;  Lv, Jingzhi;  Li, Fupeng;  Zhang, Yan;  Zeng, Guodan;  Wang, Xue;  Ma, Wen;  Hou, Guixue;  Hao, Shijie;  Liu, Chang;  Lai, Yiwei;  Liu, Panhong;  Wang, Bo;  Li, Yuxiang;  Zhang, Wenwei;  Gao, Peng;  Xie, Jun;  Esteban, Miguel A.;  Gu, Ying;  Liu, Xin;  Ji, Jiansong;  Qi, Ting;  Liu, Boxiang;  Wang, Hua;  Zhao, Yi;  Yang, Xiao;  Wang, Xiangdong;  Chen, Runsheng;  Yang, Jian;  Yin, Ye;  Wang, Jian;  Cao, Yanan;  Xu, Xun;  Liu, Longqi;  Jin, Xin;  Liu, Chuanyu 收藏  |  浏览/下载：1/0  |  提交时间：2026/05/25
	Redefining imaging genomics for the next decade 期刊论文 SCIENCE BULLETIN, 2025, 卷号: 70, 期号: 22, 页码: 3720-3723 作者:  Cen, Xiaoping;  Zou, Jiansheng;  Tong, Yahan;  Zhao, Yi;  Li, Yixue;  Yang, Huanming 收藏  |  浏览/下载：1/0  |  提交时间：2026/05/25
	NONCODE v7.0: updated lncRNA resource integrating scRNA-seq data encompassing immune baseline, development, and disease 期刊论文 NUCLEIC ACIDS RESEARCH, 2025, 页码: 8 作者:  Liu, Hongjie;  Yang, Yongsan;  Le, Xin;  Gao, Kai;  Liu, Jingjia;  Fan, Youfen;  Zeng, Xiaoxi;  Chen, Runsheng;  Zheng, Jianjun;  Zhao, Yi 收藏  |  浏览/下载：1/0  |  提交时间：2026/05/25
	The interplay between tissue-resident microbiome and host proteins by integrated multi-omics during progression of colorectal adenoma to carcinoma 期刊论文 IMETA, 2025, 页码: 37 作者:  Wu, Di;  Wang, An-Jun;  Bu, De-Chao;  Sun, Yan-Yan;  Li, Chen-Hao;  Hong, Yue-Mei;  Zhang, Shan;  Chen, Shi-Yang;  Zhou, Jin-An;  Zhang, Tian-Yi;  Yu, Min-Hao;  Ma, Yong-Jing;  Wang, Xiu-Li;  Xu, Jia;  He, Wei;  Heeschen, Christopher;  Chen, Jian-Feng;  Mao, Wen-Jun;  Ding, Hui;  Wu, Wen-Juan;  Zhao, Yi;  Wang, Hui;  Liu, Ning-Ning 收藏  |  浏览/下载：24/0  |  提交时间：2025/12/03 colorectal cancer  metagenomics  microbiota-host interaction  proteomics  tissue-resident microbiome
	LINS: A general medical Q&A framework for enhancing the quality and credibility of LLM-generated responses 期刊论文 NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20 作者:  Wang, Sheng;  Zhao, Fangyuan;  Bu, Dechao;  Lu, Yunwei;  Gong, Ming;  Liu, Hongjie;  Yang, Zhaohui;  Zeng, Xiaoxi;  Yuan, Zhiyuan;  Wan, Baoping;  Sun, Jingbo;  Wu, Yang;  Zhao, Lianhe;  Wan, Xirun;  Huang, Wei;  Wang, Tao;  Xu, Mengtong;  Luo, Jianjun;  Liu, Jingjia;  Zheng, Jianjun;  Zhang, Wei;  Zhang, Kang;  Zhang, Hongjia;  Wang, Shu;  Chen, Runsheng;  Zhao, Yi 收藏  |  浏览/下载：27/0  |  提交时间：2025/12/03
	A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16 作者:  Yang, Zhenyu;  Wang, Kai;  Zhang, Guo;  Jiang, Yuanyuan;  Zeng, Rui;  Qiao, Jingxin;  Li, Yueyue;  Deng, Xinyue;  Xia, Ziyi;  Yao, Rui;  Zeng, Xiaoxi;  Zhang, Liyun;  Zhao, Yi;  Lei, Jian;  Chen, Runsheng 收藏  |  浏览/下载：62/0  |  提交时间：2025/06/25 Structure-based bioactivity optimization  Deep-learning model  SARS-CoV-2 main protease  Molecular scaffold  Pocket-StrMod
	CIEC: Cross-tissue Immune Cell Type Enrichment and Expression Map Visualization for Cancer 期刊论文 GENOMICS PROTEOMICS & BIOINFORMATICS, 2025, 卷号: 23, 期号: 1, 页码: 8 作者:  He, Jinhua;  Luo, Haitao;  Wang, Wei;  Bu, Dechao;  Zou, Zhengkai;  Wang, Haolin;  Tang, Hongzhen;  Han, Zeping;  Luo, Wenfeng;  Shen, Jian;  Xie, Fangmei;  Zhao, Yi;  Xiang, Zhiming 收藏  |  浏览/下载：31/0  |  提交时间：2025/06/25 Cancer single-cell data  Cross-tissue analysis  Immune cell  Enrichment analysis  Expression map
	DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures 期刊论文 COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625 作者:  Qiao, Yixuan;  Yang, Rui;  Liu, Yang;  Chen, Jiaxin;  Zhao, Lianhe;  Huo, Peipei;  Wang, Zhihao;  Bu, Dechao;  Wu, Yang;  Zhao, Yi 收藏  |  浏览/下载：77/0  |  提交时间：2024/05/20 Information fusion  Deep learning  RNA -binding proteins  In vivo RNA structures  Motifs
	Enzyme Repertoires and Genomic Insights into Lycium barbarum Pectin Polysaccharide Biosynthesis 期刊论文 GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 6, 页码: 15 作者:  Yue, Haiyan;  Tang, Yiheng;  Li, Aixuan;  Zhang, Lili;  Niu, Yiwei;  Zhang, Yiming;  Wang, Hao;  Luo, Jianjun;  Zhao, Yi;  He, Shunmin;  Chen, Chang;  Chen, Runsheng 收藏  |  浏览/下载：69/0  |  提交时间：2025/06/25 Lycium barbarum  Lycium barbarum pectin polysaccharide  Phylogenetic expansion  lncRNA  Rhamnogalacturonan I rhamnosyltransferase
	HERB 2.0: an updated database integrating clinical and experimental evidence for traditional Chinese medicine 期刊论文 NUCLEIC ACIDS RESEARCH, 2024, 页码: 11 作者:  Gao, Kai;  Liu, Liu;  Lei, Shuangshuang;  Li, Zhinong;  Huo, Peipei;  Wang, Zhihao;  Dong, Lei;  Deng, Wenxin;  Bu, Dechao;  Zeng, Xiaoxi;  Li, Chun;  Zhao, Yi;  Zhang, Wei;  Wang, Wei;  Wu, Yang 收藏  |  浏览/下载：53/0  |  提交时间：2025/06/25