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DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625
作者:  Qiao, Yixuan;  Yang, Rui;  Liu, Yang;  Chen, Jiaxin;  Zhao, Lianhe;  Huo, Peipei;  Wang, Zhihao;  Bu, Dechao;  Wu, Yang;  Zhao, Yi
收藏  |  浏览/下载:16/0  |  提交时间:2024/05/20
Information fusion  Deep learning  RNA -binding proteins  In vivo RNA structures  Motifs  
Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 19
作者:  Qi, Xiaoning;  Zhao, Lianhe;  Tian, Chenyu;  Li, Yueyue;  Chen, Zhen-Lin;  Huo, Peipei;  Chen, Runsheng;  Liu, Xiaodong;  Wan, Baoping;  Yang, Shengyong;  Zhao, Yi
收藏  |  浏览/下载:2/0  |  提交时间:2024/12/06
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model 期刊论文
CELL RESEARCH, 2024, 页码: 16
作者:  Yang, Xiaodong;  Liu, Guole;  Feng, Guihai;  Bu, Dechao;  Wang, Pengfei;  Jiang, Jie;  Chen, Shubai;  Yang, Qinmeng;  Miao, Hefan;  Zhang, Yiyang;  Man, Zhenpeng;  Liang, Zhongming;  Wang, Zichen;  Li, Yaning;  Li, Zheng;  Liu, Yana;  Tian, Yao;  Liu, Wenhao;  Li, Cong;  Li, Ao;  Dong, Jingxi;  Hu, Zhilong;  Fang, Chen;  Cui, Lina;  Deng, Zixu;  Jiang, Haiping;  Cui, Wentao;  Zhang, Jiahao;  Yang, Zhaohui;  Li, Handong;  He, Xingjian;  Zhong, Liqun;  Zhou, Jiaheng;  Wang, Zijian;  Long, Qingqing;  Xu, Ping;  Wang, Hongmei;  Meng, Zhen;  Wang, Xuezhi;  Wang, Yangang;  Wang, Yong;  Zhang, Shihua;  Guo, Jingtao;  Zhao, Yi;  Zhou, Yuanchun;  Li, Fei;  Liu, Jing;  Chen, Yiqiang;  Yang, Ge;  Li, Xin
收藏  |  浏览/下载:4/0  |  提交时间:2024/12/06
dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms (vol 20, pg 446, 2022) 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 1, 页码: 1
作者:  Xu, Feng;  Wang, Yifan;  Ling, Yunchao;  Zhou, Chenfen;  Wang, Haizhou;  Teschendorff, Andrew E.;  Zhao, Yi;  Zhao, Haitao;  He, Yungang;  Zhang, Guoqing;  Yang, Zhen
收藏  |  浏览/下载:6/0  |  提交时间:2024/12/06
Benchmarking spatial clustering methods with spatially resolved transcriptomics data 期刊论文
NATURE METHODS, 2024, 页码: 25
作者:  Yuan, Zhiyuan;  Zhao, Fangyuan;  Lin, Senlin;  Zhao, Yu;  Yao, Jianhua;  Cui, Yan;  Zhang, Xiao-Yong;  Zhao, Yi
收藏  |  浏览/下载:14/0  |  提交时间:2024/05/20
Towards interpretable imaging genomics analysis: Methodological developments and applications 期刊论文
INFORMATION FUSION, 2024, 卷号: 102, 页码: 18
作者:  Cen, Xiaoping;  Dong, Wei;  Lv, Wei;  Zhao, Yi;  Dubee, Fred;  Mentis, Alexios-Fotios A.;  Jovic, Dragomirka;  Yang, Huanming;  Li, Yixue
收藏  |  浏览/下载:19/0  |  提交时间:2023/12/04
Interpretability  Imaging genomics  Genotype -phenotype association  Precision medicine  
Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer 期刊论文
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:  Cheng, Yanan;  Dong, Li;  Bu, Dechao;  Han, Lei;  Zhao, Yi;  Liu, Juntian;  Guo, Xiaojing;  Xu, Hanli;  Yu, Jinpu
收藏  |  浏览/下载:14/0  |  提交时间:2024/05/20
HBOC  breast cancer  optical genome mapping  structural variation  BRCA1/2  chromothripsis  
Streamlining spatial omics data analysis with Pysodb 期刊论文
NATURE PROTOCOLS, 2023, 页码: 72
作者:  Lin, Senlin;  Zhao, Fangyuan;  Wu, Zihan;  Yao, Jianhua;  Zhao, Yi;  Yuan, Zhiyuan
收藏  |  浏览/下载:12/0  |  提交时间:2024/05/20
Local Feature Matters: Cascade Multi-Scale MLP for Edge Segmentation of Medical Images 期刊论文
IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2023, 卷号: 22, 期号: 4, 页码: 828-835
作者:  Lv, Jinkai;  Hu, Yuyong;  Fu, Quanshui;  Hu, Yuqiang;  Lv, Lin;  Yang, Guoqing;  Li, Jinpeng;  Zhao, Yi
收藏  |  浏览/下载:18/0  |  提交时间:2023/12/04
MLP  medical image segmentation  semantic segmentation  
Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2023, 卷号: 51, 页码: 121-134
作者:  Cheng, Yanan;  Bu, Dechao;  Zhang, Qiaoling;  Sun, Rebecca;  Lyle, Stephen;  Zhao, Gang;  Dong, Li;  Li, Hui;  Zhao, Yi;  Yu, Jinpu;  Hao, Xishan
收藏  |  浏览/下载:17/0  |  提交时间:2023/12/04
Gastric cancer  Comprehensive genomic profiling  TMB  Mutational signature  Tumor metabolism