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TransSurv: Transformer-Based Survival Analysis Model Integrating Histopathological Images and Genomic Data for Colorectal Cancer 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2023, 卷号: 20, 期号: 6, 页码: 3411-3420
作者:  Lv, Zhilong;  Lin, Yuexiao;  Yan, Rui;  Wang, Ying;  Zhang, Fa
收藏  |  浏览/下载:9/0  |  提交时间:2024/05/20
Cancer  Genomics  Bioinformatics  Transformers  Tumors  Feature extraction  Prognostics and health management  Survival analysis  multi-modal learning  transformer  histopathological slides  genomic data  
Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2023, 卷号: 51, 页码: 121-134
作者:  Cheng, Yanan;  Bu, Dechao;  Zhang, Qiaoling;  Sun, Rebecca;  Lyle, Stephen;  Zhao, Gang;  Dong, Li;  Li, Hui;  Zhao, Yi;  Yu, Jinpu;  Hao, Xishan
收藏  |  浏览/下载:8/0  |  提交时间:2023/12/04
Gastric cancer  Comprehensive genomic profiling  TMB  Mutational signature  Tumor metabolism  
Cross Analysis of Genomic-Pathologic Features on Multiple Primary Hepatocellular Carcinoma 期刊论文
FRONTIERS IN GENETICS, 2022, 卷号: 13, 页码: 9
作者:  Ren, Fei;  Wang, Depin;  Zhang, Xueyuan;  Zhao, Na;  Wang, Xiaowen;  Zhang, Yu;  Li, Li
收藏  |  浏览/下载:13/0  |  提交时间:2023/07/12
hepatocellular carcinoma  whole exome sequencing  whole slide images  molecular profiling and subtyping  hepatitis B virus  
Disclosing Potential Key Genes, Therapeutic Targets and Agents for Non-Small Cell Lung Cancer: Evidence from Integrative Bioinformatics Analysis 期刊论文
VACCINES, 2022, 卷号: 10, 期号: 5, 页码: 20
作者:  Mosharaf, Md Parvez;  Reza, Md Selim;  Gov, Esra;  Mahumud, Rashidul Alam;  Mollah, Md Nurul Haque
收藏  |  浏览/下载:21/0  |  提交时间:2022/12/07
non-small cell lung cancer  gene expression profiles  molecular signatures  therapeutic targets and agents  integrated bioinformatics approaches  
A Novel Attention-Mechanism Based Cox Survival Model by Exploiting Pan-Cancer Empirical Genomic Information 期刊论文
CELLS, 2022, 卷号: 11, 期号: 9, 页码: 18
作者:  Meng, Xiangyu;  Wang, Xun;  Zhang, Xudong;  Zhang, Chaogang;  Zhang, Zhiyuan;  Zhang, Kuijie;  Wang, Shudong
收藏  |  浏览/下载:21/0  |  提交时间:2022/12/07
deep learning  survival analysis  neural networks  Cox regression  cancer prognosis  
Bioinformatics Screening of Potential Biomarkers from mRNA Expression Profiles to Discover Drug Targets and Agents for Cervical Cancer 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 7, 页码: 21
作者:  Reza, Md Selim;  Harun-Or-Roshid, Md;  Islam, Md Ariful;  Hossen, Md Alim;  Hossain, Md Tofazzal;  Feng, Shengzhong;  Xi, Wenhui;  Mollah, Md Nurul Haque;  Wei, Yanjie
收藏  |  浏览/下载:20/0  |  提交时间:2022/12/07
cervical cancer  mRNA expression profiles  key genes  candidate drugs  integrated bioinformatics analysis  
Identification of circRNA Biomarker for Gastric Cancer through Integrated Analysis 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 13
作者:  Hossain, Md. Tofazzal;  Li, Song;  Reza, Md. Selim;  Feng, Shengzhong;  Zhang, Xiaojing;  Jin, Zhe;  Wei, Yanjie;  Peng, Yin
收藏  |  浏览/下载:21/0  |  提交时间:2022/12/07
gastric cancer  circular RNA  computational approach  circRNA biomarker  circRNA-miRNA-gene interaction  
High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer 期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11, 页码: 23
作者:  Liu, Xinkui;  Wu, Yang;  Zhang, Yingying;  Bu, Dechao;  Wu, Chao;  Lu, Shan;  Huang, Zhihong;  Song, Yurong;  Zhao, Yi;  Guo, Fengying;  Ye, Peizhi;  Fu, Changgeng;  Shen, Liangliang;  Zhang, Jingyuan;  Wang, Haojia;  Duan, Xianchun;  Wu, Jiarui
收藏  |  浏览/下载:29/0  |  提交时间:2022/06/21
compound kushen injection  triple-negative breast cancer  RNA sequencing  tumor microenvironment  prognostic signature  
DeepOmix: A scalable and interpretable multi-omics deep learning framework and application in cancer survival analysis 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 2719-2725
作者:  Zhao, Lianhe;  Dong, Qiongye;  Luo, Chunlong;  Wu, Yang;  Bu, Dechao;  Qi, Xiaoning;  Luo, Yufan;  Zhao, Yi
收藏  |  浏览/下载:43/0  |  提交时间:2021/12/01
Multi-omics  Deep learning  Survival analysis  Prognosis prediction  Interpretable model  
SUFU mediates EMT and Wnt/beta-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer 期刊论文
CELL CYCLE, 2020, 页码: 14
作者:  Peng, Yin;  Zhang, Xiaojing;  Lin, Huijuan;  Deng, Shiqi;  Qin, Ying;  Yuan, Yuan;  Feng, Xianling;  Wang, Jian;  Chen, Wangchun;  Hu, Fan;  Yan, Ruibin;  Zhao, Yanqiu;  Cheng, Yulan;  Wei, Yanjie;  Fan, Xinmin;  Ashktorab, Hassan;  Smoot, Duane;  Li, Song;  Meltzer, Stephen J.;  Jin, Zhe
收藏  |  浏览/下载:54/0  |  提交时间:2020/12/10
miRNA-324-5p  SUFU negative regulator of hedgehog signaling  Wnt/beta-catenin  EMT