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A retrospective study on the mechanism underlying quick transfer from response to resistance in a repeated recurrent chordoma patient with molecular alterations treated with Palbociclib 期刊论文
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2024, 卷号: 150, 期号: 2, 页码: 9
作者:  Zhong, Nanzhe;  Yu, Dong;  Yang, Minglei;  Lu, Xingyi;  Zhang, Qiangzu;  Wei, Wei;  Jiao, Jian;  Yang, Xinghai;  Zhu, Zhi;  Chen, Su;  Xiao, Jianru
收藏  |  浏览/下载:8/0  |  提交时间:2024/05/20
Chordoma  Palbociclib  Genomic features  Drug resistance  
Towards interpretable imaging genomics analysis: Methodological developments and applications 期刊论文
INFORMATION FUSION, 2024, 卷号: 102, 页码: 18
作者:  Cen, Xiaoping;  Dong, Wei;  Lv, Wei;  Zhao, Yi;  Dubee, Fred;  Mentis, Alexios-Fotios A.;  Jovic, Dragomirka;  Yang, Huanming;  Li, Yixue
收藏  |  浏览/下载:8/0  |  提交时间:2023/12/04
Interpretability  Imaging genomics  Genotype -phenotype association  Precision medicine  
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2024, 卷号: 43, 期号: 1, 页码: 15
作者:  Lin, Ying;  Wu, Yun;  Zhang, Qiangzu;  Tu, Xunwei;  Chen, Sufang;  Pan, Junfan;  Xu, Nengluan;  Lin, Ming;  She, Peiwei;  Niu, Gang;  Chen, Yusheng;  Li, Hongru
收藏  |  浏览/下载:2/0  |  提交时间:2024/05/20
Non-small cell lung cancer  Brain metastasis  RPTOR  SPHK2  S1P  
Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer 期刊论文
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:  Cheng, Yanan;  Dong, Li;  Bu, Dechao;  Han, Lei;  Zhao, Yi;  Liu, Juntian;  Guo, Xiaojing;  Xu, Hanli;  Yu, Jinpu
收藏  |  浏览/下载:2/0  |  提交时间:2024/05/20
HBOC  breast cancer  optical genome mapping  structural variation  BRCA1/2  chromothripsis  
Review: Predictive approaches to breast cancer risk 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 11, 页码: 9
作者:  Huang, Shuai;  Xu, Jun Tao;  Yang, Mei
收藏  |  浏览/下载:2/0  |  提交时间:2024/05/20
Breast cancer  Risk factors  BRCA1/2  Polygenic risk scores  Artificial intelligence  
TransSurv: Transformer-Based Survival Analysis Model Integrating Histopathological Images and Genomic Data for Colorectal Cancer 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2023, 卷号: 20, 期号: 6, 页码: 3411-3420
作者:  Lv, Zhilong;  Lin, Yuexiao;  Yan, Rui;  Wang, Ying;  Zhang, Fa
收藏  |  浏览/下载:9/0  |  提交时间:2024/05/20
Cancer  Genomics  Bioinformatics  Transformers  Tumors  Feature extraction  Prognostics and health management  Survival analysis  multi-modal learning  transformer  histopathological slides  genomic data  
Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2023, 卷号: 51, 页码: 121-134
作者:  Cheng, Yanan;  Bu, Dechao;  Zhang, Qiaoling;  Sun, Rebecca;  Lyle, Stephen;  Zhao, Gang;  Dong, Li;  Li, Hui;  Zhao, Yi;  Yu, Jinpu;  Hao, Xishan
收藏  |  浏览/下载:8/0  |  提交时间:2023/12/04
Gastric cancer  Comprehensive genomic profiling  TMB  Mutational signature  Tumor metabolism  
Identification of Key Genes as Potential Drug Targets for Gastric Cancer 期刊论文
TSINGHUA SCIENCE AND TECHNOLOGY, 2023, 卷号: 28, 期号: 4, 页码: 649-664
作者:  Hossain, Md. Tofazzal;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载:16/0  |  提交时间:2023/07/12
gastric cancer  hub genes  candidate genes  molecular docking  candidate drugs  
Identification of circRNA biomarker for gastric cancer through integrated analysis (vol 9, 857320, 2022) 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 卷号: 10, 页码: 2
作者:  Hossain, Md. Tofazzal;  Li, Song;  Reza, Md. Selim;  Feng, Shengzhong;  Zhang, Xiaojing;  Jin, Zhe;  Wei, Yanjie;  Peng, Yin
收藏  |  浏览/下载:8/0  |  提交时间:2023/12/04
gastric cancer  circular RNA  computational approach  circRNA biomarker  circRNA-miRNA-gene interaction  
Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning 期刊论文
MEDICAL IMAGE ANALYSIS, 2023, 卷号: 87, 页码: 13
作者:  Yan, Rui;  Shen, Yijun;  Zhang, Xueyuan;  Xu, Peihang;  Wang, Jun;  Li, Jintao;  Ren, Fei;  Ye, Dingwei;  Zhou, S. Kevin
收藏  |  浏览/下载:8/0  |  提交时间:2023/12/04
Bladder cancer  Contrastive learning  Gene mutation prediction  Histopathological image analysis  Multiple instance learning