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Early detection of Parkinson's disease: Machine learning-based prediction of UPDRS Part III scores in de novo patients using smartphone assessments 期刊论文
JOURNAL OF PARKINSONS DISEASE, 2025, 页码: 12
作者:  Guo, Wei-Hang;  Yang, Xiao-Dong;  Ruan, Zheng;  Wang, Xu;  Zhang, Dan-Zuo;  Song, Shu-Chao;  Chen, Yi-Qiang;  Chan, Piu
收藏  |  浏览/下载:4/0  |  提交时间:2025/12/03
Parkinson's disease  UPDRS part III  machine learning  smartphone assessment  untreated de novo patients  motor symptoms  
Validation of Deep Learning-Based DFCNN in Extremely Large-Scale Virtual Screening and Application in Trypsin I Protease Inhibitor Discovery 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 15
作者:  Zhang, Haiping;  Lin, Xiao;  Wei, Yanjie;  Zhang, Huiling;  Liao, Linbu;  Wu, Hao;  Pan, Yi;  Wu, Xuli
收藏  |  浏览/下载:66/0  |  提交时间:2022/12/07
extremely large-scale virtual screening  deep learning  DFCNN  Trypsin I Protease  de novo drug screening  
pSite: Amino Acid Confidence Evaluation for Quality Control of De Novo Peptide Sequencing and Modification Site Localization 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 1, 页码: 119-128
作者:  Yang, Hao;  Chi, Hao;  Zhou, Wen-Jing;  Zeng, Wen-Feng;  Liu, Chao;  Wang, Rui-Min;  Wang, Zhao-Wei;  Niu, Xiu-Nan;  Chen, Zhen-Lin;  He, Si-Min
收藏  |  浏览/下载:118/0  |  提交时间:2019/12/10
tandem mass spectrometry  de novo peptide sequencing  modification site localization  phosphorylation  
Open-pNovo: De Novo Peptide Sequencing with Thousands of Protein Modifications 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2017, 卷号: 16, 期号: 2, 页码: 645-654
作者:  Yang, Hao;  Chi, Hao;  Zhou, Wen-Jing;  Zeng, Wen-Feng;  He, Kun;  Liu, Chao;  Sun, Rui-Xiang;  He, Si-Min
收藏  |  浏览/下载:89/0  |  提交时间:2019/12/12
tandem mass spectrometry  de novo peptide sequencing  dynamic programming  unexpected modifications  
De novo identification and quantification of single amino-acid variants in human brain RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction High-accuracy mapping of protein binding stability on nucleosomal DNA using a single-molecule method 期刊论文
Journal of Molecular Cell Biology, 2014, 卷号: 6, 期号: 5, 页码: 421
作者:  Su Zhiduan;  Sheng Quanhu;  Li Qingrun;  Chi Hao;  Jiang Xi;  Yan Zheng;  Fu Ning;  He Simin;  Philipp Khaitovich;  Wu Jiarui;  Zeng Rong
收藏  |  浏览/下载:47/0  |  提交时间:2023/12/04
single amino-acid variants (SAVs)  de novo  proteomics  human brain tissues  
pNovo: De novo Peptide Sequencing and Identification Using HCD Spectra 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2010, 卷号: 9, 期号: 5, 页码: 2713-2724
作者:  Chi, Hao;  Sun, Rui-Xiang;  Yang, Bing;  Song, Chun-Qing;  Wang, Le-Heng;  Liu, Chao;  Fu, Yan;  Yuan, Zuo-Fei;  Wang, Hai-Peng;  He, Si-Min;  Dong, Meng-Qiu
收藏  |  浏览/下载:100/0  |  提交时间:2019/12/16
tandem mass spectrometry  HCD  de novo sequencing  pNovo  
串联质谱的蛋白质序列鉴定技术综述 期刊论文
计算机科学与探索, 2010, 卷号: 000, 期号: 002, 页码: 97
作者:  乔彦涛;  缪佳铮;  孙世伟;  刘金刚;  卜东波
收藏  |  浏览/下载:52/0  |  提交时间:2023/12/04
蛋白质组学  串联质谱  数据库搜索方法  De  Novo算法  质谱数据库方法