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Pathway-Aware Multimodal Transformer (PAMT): Integrating Pathological Image and Gene Expression for Interpretable Cancer Survival Analysis 期刊论文
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2026, 卷号: 48, 期号: 1, 页码: 896-913
作者:  Yan, Rui;  Zhang, Xueyuan;  Jiang, Zihang;  Wang, Baizhi;  Bian, Xiuwu;  Ren, Fei;  Zhou, S. Kevin
收藏  |  浏览/下载:1/0  |  提交时间:2026/05/25
Pathology  Cancer  Transformers  Feature extraction  Data models  Biological system modeling  Analytical models  Deep learning  Semantics  Multimodal transformer  model interpretability  survival analysis  pathological image analysis  gene expression  gene expression  
The interplay between tissue-resident microbiome and host proteins by integrated multi-omics during progression of colorectal adenoma to carcinoma 期刊论文
IMETA, 2025, 页码: 37
作者:  Wu, Di;  Wang, An-Jun;  Bu, De-Chao;  Sun, Yan-Yan;  Li, Chen-Hao;  Hong, Yue-Mei;  Zhang, Shan;  Chen, Shi-Yang;  Zhou, Jin-An;  Zhang, Tian-Yi;  Yu, Min-Hao;  Ma, Yong-Jing;  Wang, Xiu-Li;  Xu, Jia;  He, Wei;  Heeschen, Christopher;  Chen, Jian-Feng;  Mao, Wen-Jun;  Ding, Hui;  Wu, Wen-Juan;  Zhao, Yi;  Wang, Hui;  Liu, Ning-Ning
收藏  |  浏览/下载:24/0  |  提交时间:2025/12/03
colorectal cancer  metagenomics  microbiota-host interaction  proteomics  tissue-resident microbiome  
A highly accurate Augmented Matched Interface and Boundary method for heat dissipation in tumor anatomies 期刊论文
JOURNAL OF THERMAL BIOLOGY, 2025, 卷号: 133, 页码: 13
作者:  Xu, Jiatian;  Guan, Zhen;  Li, Chuan
收藏  |  浏览/下载:20/0  |  提交时间:2025/12/03
Hyperthermia therapy (HT)  Pennes' bioheat equation  Augmented Matched Interface and Boundary (AMIB) method  Cancer treatments  
CIEC: Cross-tissue Immune Cell Type Enrichment and Expression Map Visualization for Cancer 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2025, 卷号: 23, 期号: 1, 页码: 8
作者:  He, Jinhua;  Luo, Haitao;  Wang, Wei;  Bu, Dechao;  Zou, Zhengkai;  Wang, Haolin;  Tang, Hongzhen;  Han, Zeping;  Luo, Wenfeng;  Shen, Jian;  Xie, Fangmei;  Zhao, Yi;  Xiang, Zhiming
收藏  |  浏览/下载:31/0  |  提交时间:2025/06/25
Cancer single-cell data  Cross-tissue analysis  Immune cell  Enrichment analysis  Expression map  
ExomiRHub: A comprehensive database for hosting and analyzing human disease-related extracellular microRNA transcriptomics data 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 3104-3116
作者:  Liu, Yang;  Min, Zhuochao;  Mo, Jing;  Ju, Zhen;  Chen, Jianliang;  Liang, Weiling;  Zhang, Lantian;  Li, Hanguang;  Chan, Godfrey Chi-Fung;  Wei, Yanjie;  Zhang, Wenliang
收藏  |  浏览/下载:85/0  |  提交时间:2024/12/06
MiRNA  Extracellular vesicle  Exosome  Cancer  Liquid biopsy  
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2024, 卷号: 43, 期号: 1, 页码: 15
作者:  Lin, Ying;  Wu, Yun;  Zhang, Qiangzu;  Tu, Xunwei;  Chen, Sufang;  Pan, Junfan;  Xu, Nengluan;  Lin, Ming;  She, Peiwei;  Niu, Gang;  Chen, Yusheng;  Li, Hongru
收藏  |  浏览/下载:75/0  |  提交时间:2024/05/20
Non-small cell lung cancer  Brain metastasis  RPTOR  SPHK2  S1P  
Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer 期刊论文
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:  Cheng, Yanan;  Dong, Li;  Bu, Dechao;  Han, Lei;  Zhao, Yi;  Liu, Juntian;  Guo, Xiaojing;  Xu, Hanli;  Yu, Jinpu
收藏  |  浏览/下载:75/0  |  提交时间:2024/05/20
HBOC  breast cancer  optical genome mapping  structural variation  BRCA1/2  chromothripsis  
TransSurv: Transformer-Based Survival Analysis Model Integrating Histopathological Images and Genomic Data for Colorectal Cancer 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2023, 卷号: 20, 期号: 6, 页码: 3411-3420
作者:  Lv, Zhilong;  Lin, Yuexiao;  Yan, Rui;  Wang, Ying;  Zhang, Fa
收藏  |  浏览/下载:105/0  |  提交时间:2024/05/20
Cancer  Genomics  Bioinformatics  Transformers  Tumors  Feature extraction  Prognostics and health management  Survival analysis  multi-modal learning  transformer  histopathological slides  genomic data  
Review: Predictive approaches to breast cancer risk 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 11, 页码: 9
作者:  Huang, Shuai;  Xu, Jun Tao;  Yang, Mei
收藏  |  浏览/下载:64/0  |  提交时间:2024/05/20
Breast cancer  Risk factors  BRCA1/2  Polygenic risk scores  Artificial intelligence  
Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2023, 卷号: 51, 页码: 121-134
作者:  Cheng, Yanan;  Bu, Dechao;  Zhang, Qiaoling;  Sun, Rebecca;  Lyle, Stephen;  Zhao, Gang;  Dong, Li;  Li, Hui;  Zhao, Yi;  Yu, Jinpu;  Hao, Xishan
收藏  |  浏览/下载:83/0  |  提交时间:2023/12/04
Gastric cancer  Comprehensive genomic profiling  TMB  Mutational signature  Tumor metabolism