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Protein Structure Prediction: Challenges, Advances, and the Shift of Research Paradigms 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2023, 卷号: 21, 期号: 5, 页码: 913-925
作者:  Huang, Bin;  Kong, Lupeng;  Wang, Chao;  Ju, Fusong;  Zhang, Qi;  Zhu, Jianwei;  Gong, Tiansu;  Zhang, Haicang;  Yu, Chungong;  Zheng, Wei-Mou;  Bu, Dongbo
收藏  |  浏览/下载:10/0  |  提交时间:2024/05/20
Protein folding  Protein structure prediction  Deep learning  Transformer  Language model  
ProALIGN: Directly Learning Alignments for Protein Structure Prediction via Exploiting Context-Specific Alignment Motifs 期刊论文
JOURNAL OF COMPUTATIONAL BIOLOGY, 2022, 页码: 14
作者:  Kong, Lupeng;  Ju, Fusong;  Zheng, Wei-mou;  Zhu, Jianwei;  Sun, Shiwei;  Xu, Jinbo;  Bu, Dongbo
收藏  |  浏览/下载:26/0  |  提交时间:2022/12/07
deep learning and protein threading  protein alignment  protein structure prediction  
FALCON2: a web server for high-quality prediction of protein tertiary structures 期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 14
作者:  Kong, Lupeng;  Ju, Fusong;  Zhang, Haicang;  Sun, Shiwei;  Bu, Dongbo
收藏  |  浏览/下载:46/0  |  提交时间:2021/12/01
Protein structure prediction  Template-based modeling  Ab initio prediction  Protein structure prediction web service  
CopulaNet: Learning residue co-evolution directly from multiple sequence alignment for protein structure prediction 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 9
作者:  Ju, Fusong;  Zhu, Jianwei;  Shao, Bin;  Kong, Lupeng;  Liu, Tie-Yan;  Zheng, Wei-Mou;  Bu, Dongbo
收藏  |  浏览/下载:42/0  |  提交时间:2021/12/01
ISSEC: inferring contacts among protein secondary structure elements using deep object detection 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 13
作者:  Zhang, Qi;  Zhu, Jianwei;  Ju, Fusong;  Kong, Lupeng;  Sun, Shiwei;  Zheng, Wei-Mou;  Bu, Dongbo
收藏  |  浏览/下载:37/0  |  提交时间:2021/12/01
Protein structure  Secondary structure elements  Inter-SSE contacts  
Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling 期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 10
作者:  Wang, Chao;  Wei, Yi;  Zhang, Haicang;  Kong, Lupeng;  Sun, Shiwei;  Zheng, Wei-Mou;  Bu, Dongbo
收藏  |  浏览/下载:90/0  |  提交时间:2019/08/16
Protein structure prediction  Energy function  Attraction-basin  Reverse Monte Carlo sampling  Monte Carlo search  Linear program  
Improving protein fold recognition by extracting fold-specific features from predicted residue-residue contacts 期刊论文
BIOINFORMATICS, 2017, 卷号: 33, 期号: 23, 页码: 3749-3757
作者:  Zhu, Jianwei;  Zhang, Haicang;  Li, Shuai Cheng;  Wang, Chao;  Kong, Lupeng;  Sun, Shiwei;  Zheng, Wei-Mou;  Bu, Dongbo
收藏  |  浏览/下载:63/0  |  提交时间:2019/12/10