Super-resolution nanoscopy by coherent control on nanoparticle emission

doi:10.1126/sciadv.aaw6579

	Super-resolution nanoscopy by coherent control on nanoparticle emission
	Liu, Congyue 1; Liu, Wei 1; Wang, Shufeng 1,2,3; Li, Hongjia 4,5; Lv, Zhilong 4,5; Zhang, Fa 4; Zhang, Donghui 6,7; Teng, Junlin 6,7; Zheng, Tao 8; Li, Donghai 9; Zhang, Mingshu 10; Xu, Pingyong 10,11; Gong, Qihuang 1,2,3
	2020-04-01
发表期刊	SCIENCE ADVANCES
ISSN	2375-2548
卷号	6 期号:16 页码:8
摘要	Super-resolution nanoscopy based on wide-field microscopic imaging provided high efficiency but limited resolution. Here, we demonstrate a general strategy to push its resolution down to -50 nm, which is close to the range of single molecular localization microscopy, without sacrificing the wide-field imaging advantage. It is done by actively and simultaneously modulating the characteristic emission of each individual emitter at high density. This method is based on the principle of excited state coherent control on single-particle two-photon fluorescence. In addition, the modulation efficiently suppresses the noise for imaging. The capability of the method is verified both in simulation and in experiments on ZnCdS quantum dot-labeled films and COS7 cells. The principle of coherent control is generally applicable to single-multiphoton imaging and various probes.
DOI	10.1126/sciadv.aaw6579
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program[2016YFB0401003] ; National Key Research and Development Program[2017YFA0504702] ; National Natural Science Foundation of China[91750203] ; National Natural Science Foundation of China[11527901] ; National Natural Science Foundation of China[11874074] ; National Natural Science Foundation of China[61775004] ; National Natural Science Foundation of China[61575005] ; National Natural Science Foundation of China[11574009] ; National Natural Science Foundation of China[31421002] ; National Natural Science Foundation of China[U1611261] ; National Natural Science Foundation of China[U1611263] ; National Natural Science Foundation of China[U1605244]
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000528276800002
出版者	AMER ASSOC ADVANCEMENT SCIENCE
引用统计	被引频次：12[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/15452
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Wang, Shufeng; Zhang, Fa; Gong, Qihuang
作者单位	1.Peking Univ, Dept Phys, State Key Lab Artificial Microstruct & Mesoscop P, Beijing 100871, Peoples R China 2.Shanxi Univ, Collaborat Innovat Ctr Extreme Opt, Taiyuan 030006, Peoples R China 3.Peking Univ, Frontiers Sci Ctr Nanooptoelect, Collaborat Innovat Ctr Quantum Matter, Beijing 100871, Peoples R China 4.Chinese Acad Sci, High Performance Comp Res Ctr, Inst Comp Technol, Beijing, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Peking Univ, Coll Life Sci, Key Lab Cell Proliferat & Differentiat, Minist Educ, Beijing 100871, Peoples R China 7.Peking Univ, Coll Life Sci, State Key Lab Membrane Biol, Beijing 100871, Peoples R China 8.Peking Univ, Acad Adv Interdisciplinary Studies, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China 9.Univ Wurzburg, Inst Phys & Theoret Chem, D-97074 Wurzburg, Germany 10.Chinese Acad Sci, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China 11.Univ Chinese Acad Sci, Coll Life Sci, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Liu, Congyue,Liu, Wei,Wang, Shufeng,et al. Super-resolution nanoscopy by coherent control on nanoparticle emission[J]. SCIENCE ADVANCES,2020,6(16):8.
APA	Liu, Congyue.,Liu, Wei.,Wang, Shufeng.,Li, Hongjia.,Lv, Zhilong.,...&Gong, Qihuang.(2020).Super-resolution nanoscopy by coherent control on nanoparticle emission.SCIENCE ADVANCES,6(16),8.
MLA	Liu, Congyue,et al."Super-resolution nanoscopy by coherent control on nanoparticle emission".SCIENCE ADVANCES 6.16(2020):8.