The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs

doi:10.1080/10408410802482008

	The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs
	He, Shunmin 1,2,3,4,5,6; Yang, Zhen 1,2,3; Skogerbo, Geir 4,5; Ren, Fei 1; Cui, Hongliang 1; Zhao, Haitao 2,3; Chen, Runsheng 1,4,5; Zhao, Yi 1
	2008
发表期刊	CRITICAL REVIEWS IN MICROBIOLOGY
ISSN	1040-841X
卷号	34 期号:3-4 页码:175-188
摘要	microRNAs (miRNAs) represent a class of noncoding RNA species, believed to be regulating gene expression by binding to complementary sites in the 3'UTRs of target mRNAs. They play important regulatory roles in various metabolic pathways in most eukaryotes. The recent discovery of virus encoded miRNAs suggests that viruses may be using them to regulate host and viral gene expression. Another class of closely related small interfering RNAs (siRNAs) also has been found within the HIV-1 genome and shown to be exerting a limited impact on virus reproduction. Additionally, an additional type of viral noncoding RNAs named small noncoding RNAs (sncRNAs) ranging from a few tens to a few hundred nucleotides in length, has also been identified. sncRNAs have a wide phylogenesis and high levels of expression, suggesting they may play an important roles in different species. Here we discuss the genomic organization, expression, conservation as well as potential function of virally encoded miRNA, siRNA, and sncRNAs.
关键词	miRNA siRNA Small noncoding RNA Viruses
DOI	10.1080/10408410802482008
收录类别	SCI
语种	英语
资助项目	National Sciences Foundation of China[30570393] ; National Sciences Foundation of China[30600729]
WOS研究方向	Microbiology
WOS类目	Microbiology
WOS记录号	WOS:000260797900005
出版者	INFORMA HEALTHCARE
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/11355
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Zhao, Yi
作者单位	1.Chinese Acad Sci, Ctr Adv Comp Technol Res, Inst Comp Technol, Bioinformat Res Grp, Beijing, Peoples R China 2.Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Liver Surg, Beijing 100037, Peoples R China 3.Chinese Acad Sci, PUMC, Beijing, Peoples R China 4.Chinese Acad Sci, Bioinformat Lab, Beijing, Peoples R China 5.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100080, Peoples R China 6.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式 GB/T 7714	He, Shunmin,Yang, Zhen,Skogerbo, Geir,et al. The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs[J]. CRITICAL REVIEWS IN MICROBIOLOGY,2008,34(3-4):175-188.
APA	He, Shunmin.,Yang, Zhen.,Skogerbo, Geir.,Ren, Fei.,Cui, Hongliang.,...&Zhao, Yi.(2008).The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs.CRITICAL REVIEWS IN MICROBIOLOGY,34(3-4),175-188.
MLA	He, Shunmin,et al."The Properties and Functions of Virus Encoded microRNA, siRNA, and Other Small Noncoding RNAs".CRITICAL REVIEWS IN MICROBIOLOGY 34.3-4(2008):175-188.