Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research

doi:10.1093/nar/gkl779

	Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research
	Chang, Suhua ; Zhang, Jiajie ; Liao, Xiaoyun ; Zhu, Xinxing ; Wang, Dahai ; Zhu, Jiang ; Feng, Tao ; Zhu, Baoli ; Gao, George F.; Wang, Jian ; Yang, Huanming ; Yu, Jun ; Wang, Jing
	2007
发表期刊	NUCLEIC ACIDS RESEARCH
ISSN	0305-1048
卷号	35 页码:D376-D380
摘要	Frequent outbreaks of highly pathogenic avian influenza and the increasing data available for comparative analysis require a central database specialized in influenza viruses (IVs). We have established the Influenza Virus Database (IVDB) to integrate information and create an analysis platform for genetic, genomic, and phylogenetic studies of the virus. IVDB hosts complete genome sequences of influenza A virus generated by Beijing Institute of Genomics (BIG) and curates all other published IV sequences after expert annotation. Our Q-Filter system classifies and ranks all nucleotide sequences into seven categories according to sequence content and integrity. IVDB provides a series of tools and viewers for comparative analysis of the viral genomes, genes, genetic polymorphisms and phylogenetic relationships. A search system has been developed for users to retrieve a combination of different data types by setting search options. To facilitate analysis of global viral transmission and evolution, the IV Sequence Distribution Tool (IVDT) has been developed to display the worldwide geographic distribution of chosen viral genotypes and to couple genomic data with epidemiological data. The BLAST, multiple sequence alignment and phylogenetic analysis tools were integrated for online data analysis. Furthermore, IVDB offers instant access to pre-computed alignments and polymorphisms of IV genes and proteins, and presents the results as SNP distribution plots and minor allele distributions. IVDB is publicly available at http://influenza.genomics.org.cn.
DOI	10.1093/nar/gkl779
收录类别	SCI
语种	英语
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
WOS记录号	WOS:000243494600078
出版者	OXFORD UNIV PRESS
引用统计	被引频次：49[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/10916
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Yu, Jun
作者单位	1.Chinese Acad Sci, Beijing Inst Genom, Beijing 101300, Peoples R China 2.Chinese Acad Sci, Inst Comp Technol, Beijing 100080, Peoples R China 3.Zhejiang Univ, James D Watson Inst Genome Sci, Hangzhou 310007, Peoples R China 4.Chinese Acad Sci, Joint Ctr Microbial Genom, Beijing 101300, Peoples R China 5.Chinese Acad Sci, Inst Microbiol, Ctr Mol Virol, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Chang, Suhua,Zhang, Jiajie,Liao, Xiaoyun,et al. Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research[J]. NUCLEIC ACIDS RESEARCH,2007,35:D376-D380.
APA	Chang, Suhua.,Zhang, Jiajie.,Liao, Xiaoyun.,Zhu, Xinxing.,Wang, Dahai.,...&Wang, Jing.(2007).Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research.NUCLEIC ACIDS RESEARCH,35,D376-D380.
MLA	Chang, Suhua,et al."Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research".NUCLEIC ACIDS RESEARCH 35(2007):D376-D380.