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A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 12, 页码: 20
作者:  Zhang, Haiping;  Yang, Yang;  Li, Junxin;  Wang, Min;  Saravanan, Konda Mani;  Wei, Jinli;  Ng, Justin Tze-Yang;  Hossain, Md Tofazzal;  Liu, Maoxuan;  Zhang, Huiling;  Ren, Xiaohu;  Pan, Yi;  Peng, Yin;  Shi, Yi;  Wan, Xiaochun;  Liu, Yingxia;  Wei, Yanjie
收藏  |  浏览/下载:45/0  |  提交时间:2021/12/01
Compressed sensing improved iterative reconstruction-reprojection algorithm for electron tomography 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 页码: 19
作者:  Li, Lun;  Han, Renmin;  Zhang, Zhaotian;  Guo, Tiande;  Liu, Zhiyong;  Zhang, Fa
收藏  |  浏览/下载:33/0  |  提交时间:2021/12/01
Electron tomography  Compressed sensing  Matching pursuit  Iterative reconstruction-reprojection  
ISSEC: inferring contacts among protein secondary structure elements using deep object detection 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 13
作者:  Zhang, Qi;  Zhu, Jianwei;  Ju, Fusong;  Kong, Lupeng;  Sun, Shiwei;  Zheng, Wei-Mou;  Bu, Dongbo
收藏  |  浏览/下载:33/0  |  提交时间:2021/12/01
Protein structure  Secondary structure elements  Inter-SSE contacts  
Deep Learning in Proteomics 期刊论文
PROTEOMICS, 2020, 页码: 21
作者:  Wen, Bo;  Zeng, Wen-Feng;  Liao, Yuxing;  Shi, Zhiao;  Savage, Sara R.;  Jiang, Wen;  Zhang, Bing
收藏  |  浏览/下载:34/0  |  提交时间:2021/12/01
bioinformatics  deep learning  proteomics  
Spark-based parallel calculation of 3D fourier shell correlation for macromolecule structure local resolution estimation 期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 页码: 18
作者:  Lue, Yongchun;  Zeng, Xiangrui;  Tian, Xinhui;  Shi, Xiao;  Wang, Hui;  Zheng, Xiaohui;  Liu, Xiaodong;  Zhao, Xiaofang;  Gao, Xin;  Xu, Min
收藏  |  浏览/下载:58/0  |  提交时间:2020/12/10
3D local Fourier shell correlation  3D local resolution map  Key-value data  Spark  3D array partition  
CT-TEE Image Registration for Surgical Navigation of Congenital Heart Disease Based on a Cycle Adversarial Network 期刊论文
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE, 2020, 卷号: 2020, 页码: 8
作者:  Lu, Yunfei;  Li, Bing;  Liu, Ningtao;  Chen, Jia-Wei;  Xiao, Li;  Gou, Shuiping;  Chen, Linlin;  Huang, Meiping;  Zhuang, Jian
收藏  |  浏览/下载:64/0  |  提交时间:2020/12/10
Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov 期刊论文
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2020, 页码: 9
作者:  Zhang, Haiping;  Saravanan, Konda Mani;  Yang, Yang;  Hossain, Md Tofazzal;  Li, Junxin;  Ren, Xiaohu;  Pan, Yi;  Wei, Yanjie
收藏  |  浏览/下载:57/0  |  提交时间:2020/12/10
Coronavirus  Deep learning  Drug screening  Homology modeling  3C-like protease