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Attention-Guided Residual U-Net with SE Connection and ASPP for Watershed-Based Cell Segmentation in Microscopy Images 期刊论文
JOURNAL OF COMPUTATIONAL BIOLOGY, 2024, 页码: 13
作者:  Niyogisubizo, Jovial;  Zhao, Keliang;  Meng, Jintao;  Pan, Yi;  Didi, Rosiy Adi;  Wei, Yanjie
收藏  |  浏览/下载：2/0  |  提交时间：2024/12/06
cell segmentation  deep learning  watershed segmentation  bright-field microscopy  iPS cell reprogramming  attention mechanism  
A new paradigm for applying deep learning to protein-ligand interaction prediction 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 12
作者:  Wang, Zechen;  Wang, Sheng;  Li, Yangyang;  Guo, Jingjing;  Wei, Yanjie;  Mu, Yuguang;  Zheng, Liangzhen;  Li, Weifeng
收藏  |  浏览/下载：2/0  |  提交时间：2024/12/06
protein-ligand interaction  scoring function  deep learning  graph neural network  
Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity 期刊论文
METHODS, 2024, 卷号: 224, 页码: 35-46
作者:  Huang, Qingsheng;  Peng, Yin;  Peng, Yuefeng;  Lin, Huijuan;  Deng, Shiqi;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载：2/0  |  提交时间：2024/12/06
XIAP  Apoptosis  Antagonist  Smac mimetic  Caspase-3  Caspase-9  
A Weakly Supervised Learning Method for Cell Detection and Tracking Using Incomplete Initial Annotations 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 28
作者:  Wu, Hao;  Niyogisubizo, Jovial;  Zhao, Keliang;  Meng, Jintao;  Xi, Wenhui;  Li, Hongchang;  Pan, Yi;  Wei, Yanjie
收藏  |  浏览/下载：12/0  |  提交时间：2024/05/20
cell detection  cell tracking  deep learning  weakly supervised learning  iPS cell reprogramming  brightfield microscopy  
JCcirc: circRNA full-length sequence assembly through integrated junction contigs 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2023, 卷号: 24, 期号: 6, 页码: 11
作者:  Zhang, Jingjing;  Zhang, Huiling;  Ju, Zhen;  Peng, Yin;  Pan, Yi;  Xi, Wenhui;  Wei, Yanjie
收藏  |  浏览/下载：12/0  |  提交时间：2024/05/20
circRNA  full-length sequence  transcriptome  junction contig  
Identification of Key Genes as Potential Drug Targets for Gastric Cancer 期刊论文
TSINGHUA SCIENCE AND TECHNOLOGY, 2023, 卷号: 28, 期号: 4, 页码: 649-664
作者:  Hossain, Md. Tofazzal;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载：25/0  |  提交时间：2023/07/12
gastric cancer  hub genes  candidate genes  molecular docking  candidate drugs  
Circ_CEA promotes the interaction between the p53 and cyclin-dependent kinases 1 as a scaffold to inhibit the apoptosis of gastric cancer 期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 9, 页码: 15
作者:  Yuan, Yuan;  Zhang, Xiaojing;  Du, Kaining;  Zhu, Xiaohui;  Chang, Shanshan;  Chen, Yang;  Xu, Yidan;  Sun, Jiachun;  Luo, Xiaonuan;  Deng, Shiqi;  Qin, Ying;  Feng, Xianling;  Wei, Yanjie;  Fan, Xinmin;  Liu, Ziyang;  Zheng, Baixin;  Ashktorab, Hassan;  Smoot, Duane;  Li, Song;  Xie, Xiaoxun;  Jin, Zhe;  Peng, Yin
收藏  |  浏览/下载：23/0  |  提交时间：2023/07/12
DeepBindBC: A practical deep learning method for identifying native-like protein-ligand complexes in virtual screening 期刊论文
METHODS, 2022, 卷号: 205, 页码: 247-262
作者:  Zhang, Haiping;  Zhang, Tingting;  Saravanan, Konda Mani;  Liao, Linbu;  Wu, Hao;  Zhang, Haishan;  Zhang, Huiling;  Pan, Yi;  Wu, Xuli;  Wei, Yanjie
收藏  |  浏览/下载：24/0  |  提交时间：2023/07/12
Native like protein-ligand  Drug virtual screening  ResNet  Deep learning  Human pancreatic alpha amylase inhibitor  
Validation of Deep Learning-Based DFCNN in Extremely Large-Scale Virtual Screening and Application in Trypsin I Protease Inhibitor Discovery 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 15
作者:  Zhang, Haiping;  Lin, Xiao;  Wei, Yanjie;  Zhang, Huiling;  Liao, Linbu;  Wu, Hao;  Pan, Yi;  Wu, Xuli
收藏  |  浏览/下载：33/0  |  提交时间：2022/12/07
extremely large-scale virtual screening  deep learning  DFCNN  Trypsin I Protease  de novo drug screening  
Reconstruction of Full-Length circRNA Sequences Using Chimeric Alignment Information 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 12, 页码: 15
作者:  Hossain, Md. Tofazzal;  Zhang, Jingjing;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载：29/0  |  提交时间：2022/12/07
circular RNA  reconstruction of circRNA sequence  full-length sequence