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A Survey on Causal Reinforcement Learning 期刊论文
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 页码: 21
作者:  Zeng, Yan;  Cai, Ruichu;  Sun, Fuchun;  Huang, Libo;  Hao, Zhifeng
收藏  |  浏览/下载：4/0  |  提交时间：2025/06/25
Cause effect analysis  Surveys  Mathematical models  Drugs  Sun  Reviews  Reinforcement learning  Decision making  Data models  Computer science  Causal discovery  causal inference  causal reinforcement learning (CRL)  Markov decision process (MDP)  sequential decision-making  
Attention-Guided Residual U-Net with SE Connection and ASPP for Watershed-Based Cell Segmentation in Microscopy Images 期刊论文
JOURNAL OF COMPUTATIONAL BIOLOGY, 2024, 页码: 13
作者:  Niyogisubizo, Jovial;  Zhao, Keliang;  Meng, Jintao;  Pan, Yi;  Didi, Rosiy Adi;  Wei, Yanjie
收藏  |  浏览/下载：31/0  |  提交时间：2024/12/06
cell segmentation  deep learning  watershed segmentation  bright-field microscopy  iPS cell reprogramming  attention mechanism  
A new paradigm for applying deep learning to protein-ligand interaction prediction 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 12
作者:  Wang, Zechen;  Wang, Sheng;  Li, Yangyang;  Guo, Jingjing;  Wei, Yanjie;  Mu, Yuguang;  Zheng, Liangzhen;  Li, Weifeng
收藏  |  浏览/下载：19/0  |  提交时间：2024/12/06
protein-ligand interaction  scoring function  deep learning  graph neural network  
Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity 期刊论文
METHODS, 2024, 卷号: 224, 页码: 35-46
作者:  Huang, Qingsheng;  Peng, Yin;  Peng, Yuefeng;  Lin, Huijuan;  Deng, Shiqi;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载：19/0  |  提交时间：2024/12/06
XIAP  Apoptosis  Antagonist  Smac mimetic  Caspase-3  Caspase-9  
A Weakly Supervised Learning Method for Cell Detection and Tracking Using Incomplete Initial Annotations 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 28
作者:  Wu, Hao;  Niyogisubizo, Jovial;  Zhao, Keliang;  Meng, Jintao;  Xi, Wenhui;  Li, Hongchang;  Pan, Yi;  Wei, Yanjie
收藏  |  浏览/下载：39/0  |  提交时间：2024/05/20
cell detection  cell tracking  deep learning  weakly supervised learning  iPS cell reprogramming  brightfield microscopy  
JCcirc: circRNA full-length sequence assembly through integrated junction contigs 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2023, 卷号: 24, 期号: 6, 页码: 11
作者:  Zhang, Jingjing;  Zhang, Huiling;  Ju, Zhen;  Peng, Yin;  Pan, Yi;  Xi, Wenhui;  Wei, Yanjie
收藏  |  浏览/下载：37/0  |  提交时间：2024/05/20
circRNA  full-length sequence  transcriptome  junction contig  
Identification of Key Genes as Potential Drug Targets for Gastric Cancer 期刊论文
TSINGHUA SCIENCE AND TECHNOLOGY, 2023, 卷号: 28, 期号: 4, 页码: 649-664
作者:  Hossain, Md. Tofazzal;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载：44/0  |  提交时间：2023/07/12
gastric cancer  hub genes  candidate genes  molecular docking  candidate drugs  
Circ_CEA promotes the interaction between the p53 and cyclin-dependent kinases 1 as a scaffold to inhibit the apoptosis of gastric cancer 期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 9, 页码: 15
作者:  Yuan, Yuan;  Zhang, Xiaojing;  Du, Kaining;  Zhu, Xiaohui;  Chang, Shanshan;  Chen, Yang;  Xu, Yidan;  Sun, Jiachun;  Luo, Xiaonuan;  Deng, Shiqi;  Qin, Ying;  Feng, Xianling;  Wei, Yanjie;  Fan, Xinmin;  Liu, Ziyang;  Zheng, Baixin;  Ashktorab, Hassan;  Smoot, Duane;  Li, Song;  Xie, Xiaoxun;  Jin, Zhe;  Peng, Yin
收藏  |  浏览/下载：45/0  |  提交时间：2023/07/12
DeepBindBC: A practical deep learning method for identifying native-like protein-ligand complexes in virtual screening 期刊论文
METHODS, 2022, 卷号: 205, 页码: 247-262
作者:  Zhang, Haiping;  Zhang, Tingting;  Saravanan, Konda Mani;  Liao, Linbu;  Wu, Hao;  Zhang, Haishan;  Zhang, Huiling;  Pan, Yi;  Wu, Xuli;  Wei, Yanjie
收藏  |  浏览/下载：46/0  |  提交时间：2023/07/12
Native like protein-ligand  Drug virtual screening  ResNet  Deep learning  Human pancreatic alpha amylase inhibitor  
Validation of Deep Learning-Based DFCNN in Extremely Large-Scale Virtual Screening and Application in Trypsin I Protease Inhibitor Discovery 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 15
作者:  Zhang, Haiping;  Lin, Xiao;  Wei, Yanjie;  Zhang, Huiling;  Liao, Linbu;  Wu, Hao;  Pan, Yi;  Wu, Xuli
收藏  |  浏览/下载：52/0  |  提交时间：2022/12/07
extremely large-scale virtual screening  deep learning  DFCNN  Trypsin I Protease  de novo drug screening