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DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625
作者:  Qiao, Yixuan;  Yang, Rui;  Liu, Yang;  Chen, Jiaxin;  Zhao, Lianhe;  Huo, Peipei;  Wang, Zhihao;  Bu, Dechao;  Wu, Yang;  Zhao, Yi
收藏  |  浏览/下载：11/0  |  提交时间：2024/05/20
Information fusion  Deep learning  RNA -binding proteins  In vivo RNA structures  Motifs  
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2024, 卷号: 43, 期号: 1, 页码: 15
作者:  Lin, Ying;  Wu, Yun;  Zhang, Qiangzu;  Tu, Xunwei;  Chen, Sufang;  Pan, Junfan;  Xu, Nengluan;  Lin, Ming;  She, Peiwei;  Niu, Gang;  Chen, Yusheng;  Li, Hongru
收藏  |  浏览/下载：7/0  |  提交时间：2024/05/20
Non-small cell lung cancer  Brain metastasis  RPTOR  SPHK2  S1P  
Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer 期刊论文
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:  Cheng, Yanan;  Dong, Li;  Bu, Dechao;  Han, Lei;  Zhao, Yi;  Liu, Juntian;  Guo, Xiaojing;  Xu, Hanli;  Yu, Jinpu
收藏  |  浏览/下载：6/0  |  提交时间：2024/05/20
HBOC  breast cancer  optical genome mapping  structural variation  BRCA1/2  chromothripsis  
Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2023, 卷号: 51, 页码: 121-134
作者:  Cheng, Yanan;  Bu, Dechao;  Zhang, Qiaoling;  Sun, Rebecca;  Lyle, Stephen;  Zhao, Gang;  Dong, Li;  Li, Hui;  Zhao, Yi;  Yu, Jinpu;  Hao, Xishan
收藏  |  浏览/下载：13/0  |  提交时间：2023/12/04
Gastric cancer  Comprehensive genomic profiling  TMB  Mutational signature  Tumor metabolism  
Identification of Key Genes as Potential Drug Targets for Gastric Cancer 期刊论文
TSINGHUA SCIENCE AND TECHNOLOGY, 2023, 卷号: 28, 期号: 4, 页码: 649-664
作者:  Hossain, Md. Tofazzal;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载：21/0  |  提交时间：2023/07/12
gastric cancer  hub genes  candidate genes  molecular docking  candidate drugs  
Circ_CEA promotes the interaction between the p53 and cyclin-dependent kinases 1 as a scaffold to inhibit the apoptosis of gastric cancer 期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 9, 页码: 15
作者:  Yuan, Yuan;  Zhang, Xiaojing;  Du, Kaining;  Zhu, Xiaohui;  Chang, Shanshan;  Chen, Yang;  Xu, Yidan;  Sun, Jiachun;  Luo, Xiaonuan;  Deng, Shiqi;  Qin, Ying;  Feng, Xianling;  Wei, Yanjie;  Fan, Xinmin;  Liu, Ziyang;  Zheng, Baixin;  Ashktorab, Hassan;  Smoot, Duane;  Li, Song;  Xie, Xiaoxun;  Jin, Zhe;  Peng, Yin
收藏  |  浏览/下载：19/0  |  提交时间：2023/07/12
Disclosing Potential Key Genes, Therapeutic Targets and Agents for Non-Small Cell Lung Cancer: Evidence from Integrative Bioinformatics Analysis 期刊论文
VACCINES, 2022, 卷号: 10, 期号: 5, 页码: 20
作者:  Mosharaf, Md Parvez;  Reza, Md Selim;  Gov, Esra;  Mahumud, Rashidul Alam;  Mollah, Md Nurul Haque
收藏  |  浏览/下载：26/0  |  提交时间：2022/12/07
non-small cell lung cancer  gene expression profiles  molecular signatures  therapeutic targets and agents  integrated bioinformatics approaches  
Bioinformatics Screening of Potential Biomarkers from mRNA Expression Profiles to Discover Drug Targets and Agents for Cervical Cancer 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 7, 页码: 21
作者:  Reza, Md Selim;  Harun-Or-Roshid, Md;  Islam, Md Ariful;  Hossen, Md Alim;  Hossain, Md Tofazzal;  Feng, Shengzhong;  Xi, Wenhui;  Mollah, Md Nurul Haque;  Wei, Yanjie
收藏  |  浏览/下载：25/0  |  提交时间：2022/12/07
cervical cancer  mRNA expression profiles  key genes  candidate drugs  integrated bioinformatics analysis  
Z16b, a natural compound from Ganoderma cochlear is a novel RyR2 stabilizer preventing catecholaminergic polymorphic ventricular tachycardia 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:  Wan, Jiang-fan;  Wang, Gang;  Qin, Fu-ying;  Huang, Dan-ling;  Wang, Yan;  Su, Ai-ling;  Zhang, Hai-ping;  Liu, Yang;  Zeng, Shao-yin;  Wei, Chao-liang;  Cheng, Yong-xian;  Liu, Jie
收藏  |  浏览/下载：32/0  |  提交时间：2022/12/07
arrhythmia  catecholaminergic polymorphic ventricular tachycardia  natural product  ryanodine receptor  induced pluripotent stem cell-derived cardiomyocytes  
Codon usage patterns across seven Rosales species 期刊论文
BMC PLANT BIOLOGY, 2022, 卷号: 22, 期号: 1, 页码: 10
作者:  Zhang, Yao;  Shen, Zenan;  Meng, Xiangrui;  Zhang, Liman;  Liu, Zhiguo;  Liu, Mengjun;  Zhang, Fa;  Zhao, Jin
收藏  |  浏览/下载：23/0  |  提交时间：2022/12/07
Rosales  Codon usage bias  Natural selection  Evolutionary relationships