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Identification of Key Genes as Potential Drug Targets for Gastric Cancer 期刊论文
TSINGHUA SCIENCE AND TECHNOLOGY, 2023, 卷号: 28, 期号: 4, 页码: 649-664
作者:  Hossain, Md. Tofazzal;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载:16/0  |  提交时间:2023/07/12
gastric cancer  hub genes  candidate genes  molecular docking  candidate drugs  
Validation of Deep Learning-Based DFCNN in Extremely Large-Scale Virtual Screening and Application in Trypsin I Protease Inhibitor Discovery 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 15
作者:  Zhang, Haiping;  Lin, Xiao;  Wei, Yanjie;  Zhang, Huiling;  Liao, Linbu;  Wu, Hao;  Pan, Yi;  Wu, Xuli
收藏  |  浏览/下载:23/0  |  提交时间:2022/12/07
extremely large-scale virtual screening  deep learning  DFCNN  Trypsin I Protease  de novo drug screening  
Reconstruction of Full-Length circRNA Sequences Using Chimeric Alignment Information 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 12, 页码: 15
作者:  Hossain, Md. Tofazzal;  Zhang, Jingjing;  Reza, Md. Selim;  Peng, Yin;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载:19/0  |  提交时间:2022/12/07
circular RNA  reconstruction of circRNA sequence  full-length sequence  
Bioinformatics Screening of Potential Biomarkers from mRNA Expression Profiles to Discover Drug Targets and Agents for Cervical Cancer 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 7, 页码: 21
作者:  Reza, Md Selim;  Harun-Or-Roshid, Md;  Islam, Md Ariful;  Hossen, Md Alim;  Hossain, Md Tofazzal;  Feng, Shengzhong;  Xi, Wenhui;  Mollah, Md Nurul Haque;  Wei, Yanjie
收藏  |  浏览/下载:20/0  |  提交时间:2022/12/07
cervical cancer  mRNA expression profiles  key genes  candidate drugs  integrated bioinformatics analysis  
Evaluation of CircRNA Sequence Assembly Methods Using Long Reads 期刊论文
FRONTIERS IN GENETICS, 2022, 卷号: 13, 页码: 12
作者:  Zhang, Jingjing;  Hossain, Md. Tofazzal;  Liu, Weiguo;  Peng, Yin;  Pan, Yi;  Wei, Yanjie
收藏  |  浏览/下载:19/0  |  提交时间:2022/12/07
circRNA  full-length sequences  short reads  long reads  assembly  
An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2 期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 13
作者:  Zhang, Haiping;  Li, Junxin;  Saravanan, Konda Mani;  Wu, Hao;  Wang, Zhichao;  Wu, Du;  Wei, Yanjie;  Lu, Zhen;  Chen, Youhai H.;  Wan, Xiaochun;  Pan, Yi
收藏  |  浏览/下载:30/0  |  提交时间:2022/06/21
TIPE2  UM-164  virtual screening  deep learning  molecular dynamics simulation  
COMTOP: Protein Residue-Residue Contact Prediction through Mixed Integer Linear Optimization 期刊论文
MEMBRANES, 2021, 卷号: 11, 期号: 7, 页码: 21
作者:  Reza, Md Selim;  Zhang, Huiling;  Hossain, Md Tofazzal;  Jin, Langxi;  Feng, Shengzhong;  Wei, Yanjie
收藏  |  浏览/下载:36/0  |  提交时间:2021/12/01
protein residue-residue contact  contact prediction  mixed integer linear programming  machine learning  protein sequence