Genome-Wide Identification and Characterization of Long Non-Coding RNAs from Mulberry (Morus notabilis) RNA-seq Data

doi:10.3390/genes7030011

	Genome-Wide Identification and Characterization of Long Non-Coding RNAs from Mulberry (Morus notabilis) RNA-seq Data
	Song, Xiaobo 1,2; Sun, Liang 3; Luo, Haitao 3; Ma, Qingguo 2; Zhao, Yi 3,4; Pei, Dong 2
	2016-03-01
发表期刊	GENES
ISSN	2073-4425
卷号	7 期号:3 页码:13
摘要	Numerous sources of evidence suggest that most of the eukaryotic genome is transcribed into protein-coding mRNAs and also into a large number of non-coding RNAs (ncRNAs). Long ncRNAs (lncRNAs), a group consisting of ncRNAs longer than 200 nucleotides, have been found to play critical roles in transcriptional, post-transcriptional, and epigenetic gene regulation across all kingdoms of life. However, lncRNAs and their regulatory roles remain poorly characterized in plants, especially in woody plants. In this paper, we used a computational approach to identify novel lncRNAs from a published RNA-seq data set and analyzed their sequences and expression patterns. In total, 1133 novel lncRNAs were identified in mulberry, and 106 of these lncRNAs displayed a predominant tissue-specific expression in the five major tissues investigated. Additionally, functional predictions revealed that tissue-specific lncRNAs adjacent to protein-coding genes might play important regulatory roles in the development of floral organ and root in mulberry. The pipeline used in this study would be useful for the identification of lncRNAs obtained from other deep sequencing data. Furthermore, the predicted lncRNAs would be beneficial towards an understanding of the variations in gene expression in plants.
关键词	lncRNAs Morus notabilis RNA-seq
DOI	10.3390/genes7030011
收录类别	SCI
语种	英语
资助项目	Special Research for Public Welfare in Forestry Industry[201304712] ; National Natural Science Foundation of China[31171933]
WOS研究方向	Genetics & Heredity
WOS类目	Genetics & Heredity
WOS记录号	WOS:000373531300001
出版者	MDPI AG
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/8453
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Pei, Dong
作者单位	1.Beijing Forestry Univ, Coll Biol Sci & Technol, Beijing 100083, Peoples R China 2.Chinese Acad Forestry, Res Inst Forestry, State Key Lab Tree Genet & Breeding, Beijing 100091, Peoples R China 3.Chinese Acad Sci, Inst Comp Technol, Key Lab Intelligent Informat Proc, Beijing 100190, Peoples R China 4.Chinese Acad Sci, Inst Comp Technol, LuoYang Branch, Precis Med Ctr,Res Inst Informat Ind LuoYang, Luoyang 471000, Peoples R China
推荐引用方式 GB/T 7714	Song, Xiaobo,Sun, Liang,Luo, Haitao,et al. Genome-Wide Identification and Characterization of Long Non-Coding RNAs from Mulberry (Morus notabilis) RNA-seq Data[J]. GENES,2016,7(3):13.
APA	Song, Xiaobo,Sun, Liang,Luo, Haitao,Ma, Qingguo,Zhao, Yi,&Pei, Dong.(2016).Genome-Wide Identification and Characterization of Long Non-Coding RNAs from Mulberry (Morus notabilis) RNA-seq Data.GENES,7(3),13.
MLA	Song, Xiaobo,et al."Genome-Wide Identification and Characterization of Long Non-Coding RNAs from Mulberry (Morus notabilis) RNA-seq Data".GENES 7.3(2016):13.