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NONCODEV5: a comprehensive annotation database for long non-coding RNAs
Fang, ShuangSang1,2; Zhang, LiLi2,3; Guo, JinCheng1,4; Niu, YiWei2,3; Wu, Yang1; Li, Hui1; Zhao, Lian He1,2; Li, Xi Yuan1; Teng, Xue Yi2,3; Sun, XianHui2,3; Sun, Liang1; Zhang, Michael Q.5; Chen, RunSheng3; Zhao, Yi1,6
2018-01-04
发表期刊NUCLEIC ACIDS RESEARCH
ISSN0305-1048
卷号46期号:D1页码:D308-D314
摘要NONCODE (http://www.bioinfo.org/noncode) is a systematic database that is dedicated to presenting the most complete collection and annotation of non-coding RNAs (ncRNAs), especially long non-coding RNAs (lncRNAs). Since NONCODE 2016 was released two years ago, the amount of novel identified ncRNAs has been enlarged by the reduced cost of next-generation sequencing, which has produced an explosion of newly identified data. The third-generation sequencing revolution has also offered longer and more accurate annotations. Moreover, accumulating evidence confirmed by biological experiments has provided more comprehensive knowledge of lncRNA functions. The ncRNA data set was expanded by collecting newly identified ncRNAs from literature published over the past two years and integration of the latest versions of RefSeq and Ensembl. Additionally, pig was included in the database for the first time, bringing the total number of species to 17. The number of lncRNAs in NONCODEv5 increased from 527 336 to 548 640. NONCODEv5 also introduced three important new features: (i) human lncRNA-disease relationships and single nucleotide polymorphism-lncRNA-disease relationships were constructed; (ii) human exosome lncRNA expression profiles were displayed; (iii) the RNA secondary structures of NONCODE human transcripts were predicted. NONCODEv5 is also accessible through http://www.noncode.org/.
DOI10.1093/nar/gkx1107
收录类别SCI
语种英语
资助项目National Natural Science Foundation of China[31371320] ; National Natural Science Foundation of China[31401119] ; National Natural Science Foundation of China[31501066] ; National Science Foundation for Young Scholars[31701141] ; National Science Foundation for Young Scholars[31701149]
WOS研究方向Biochemistry & Molecular Biology
WOS类目Biochemistry & Molecular Biology
WOS记录号WOS:000419550700047
出版者OXFORD UNIV PRESS
引用统计
被引频次:351[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://119.78.100.204/handle/2XEOYT63/6261
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Chen, RunSheng; Zhao, Yi
作者单位1.Chinese Acad Sci, Inst Comp Technol, Adv Comp Res Ctr, Key Lab Intelligent Informat Proc, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Inst Biophys, CAS Key Lab RNA Biol, Beijing 100101, Peoples R China
4.Shantou Univ, Med Coll, Dept Biochem & Mol Biol, Shantou 515041, Peoples R China
5.Tsinghua Univ, Sch Med, Ctr Synthet & Syst Biol,TNLIST Dept Automat, MOE Key Lab Bioinformat & Bioinformat Div, Beijing 100084, Peoples R China
6.Chinese Acad Sci, Inst Comp Technol, LuoYang Branch, Luoyang, Peoples R China
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Fang, ShuangSang,Zhang, LiLi,Guo, JinCheng,et al. NONCODEV5: a comprehensive annotation database for long non-coding RNAs[J]. NUCLEIC ACIDS RESEARCH,2018,46(D1):D308-D314.
APA Fang, ShuangSang.,Zhang, LiLi.,Guo, JinCheng.,Niu, YiWei.,Wu, Yang.,...&Zhao, Yi.(2018).NONCODEV5: a comprehensive annotation database for long non-coding RNAs.NUCLEIC ACIDS RESEARCH,46(D1),D308-D314.
MLA Fang, ShuangSang,et al."NONCODEV5: a comprehensive annotation database for long non-coding RNAs".NUCLEIC ACIDS RESEARCH 46.D1(2018):D308-D314.
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