Structural Brain Connectivity Guided Optimal Contact Selection for Deep Brain Stimulation of the Subthalamic Nucleus

doi:10.1016/j.wneu.2024.05.150

	Structural Brain Connectivity Guided Optimal Contact Selection for Deep Brain Stimulation of the Subthalamic Nucleus
	Liu, Jiali 1; Chen, Shouxuan 1; Chen, Jianwei 1; Wang, Bo 1; Zhang, Qiusheng 1; Xiao, Linxia 2; Cai, Xiaodong 1; Zhang, Doudou 1
	2024-08-01
发表期刊	WORLD NEUROSURGERY
ISSN	1878-8750
卷号	188 页码:E546-E554
摘要	- BACKGROUND: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy in ameliorating the motor symptoms of Parkinson disease. However, postoperative optimal contact selection is crucial for achieving the best outcome of deep brain stimulation of the subthalamic nucleus surgery, but the process is currently a trial-and-error and time-consuming procedure that relies heavily on surgeons ' clinical experience.- METHODS: In this study, we propose a structural brain connectivity guided optimal contact selection method for deep brain stimulation of the subthalamic nucleus. Firstly, we reconstruct the DBS electrode location and estimate the stimulation range using volume of tissue activated from each DBS contact. Then, we extract the structural connectivity features by concatenating fractional anisotropy and the number of streamlines features of activated regions and the whole brain regions. Finally, we use a convolutional neural network with convolutional block attention module to identify the structural connectivity features for the optimal contact selection.- RESULTS: We review the data of 800 contacts from 100 patients with Parkinson disease for the experiment. The proposed method achieves promising results, with the average accuracy of 97.63%, average precision of 94.50%, average recall of 94.46%, and average specificity of 98.18%, respectively. Our method can provide the suggestion for optimal contact selection. - CONCLUSIONS: Our proposed method can improve the efficiency and accuracy of DBS optimal contact selection, reduce the dependence on surgeons' experience, and has the potential to facilitate the development of advanced DBS technology.
关键词	Convolutional neural network Optimal contact selection Parkinson disease Structural brain connectivity STN-DBS surgery Volumes of tissue activated
DOI	10.1016/j.wneu.2024.05.150
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[62303442] ; Guangdong Basic, Applied Basic Research Foundation[2022A1515110996] ; China Postdoctoral Science Foundation[2023M733655] ; Shenzhen Fundamental Research Program[JCYJ20230807115203006] ; Shenzhen Fundamental Research Program[JCYJ20230807115301003] ; Shenzhen Fundamental Research Program[JCYJ20210324103014037]
WOS研究方向	Neurosciences & Neurology ; Surgery
WOS类目	Clinical Neurology ; Surgery
WOS记录号	WOS:001270829300001
出版者	ELSEVIER SCIENCE INC
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/39833
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Xiao, Linxia
作者单位	1.Shenzhen Univ, Shenzhen Peoples Hosp 2, Dept Neurosurg, Shenzhen Key Lab Neurosurg,Affiliated Hosp 1, Shenzhen, Peoples R China 2.Chinese Acad Sci, Shenzhen Inst Adv Technol, Joint Engn Res Ctr Hlth Big Data Intelligent Anal, Ctr High Performance Comp, Shenzhen, Peoples R China
推荐引用方式 GB/T 7714	Liu, Jiali,Chen, Shouxuan,Chen, Jianwei,et al. Structural Brain Connectivity Guided Optimal Contact Selection for Deep Brain Stimulation of the Subthalamic Nucleus[J]. WORLD NEUROSURGERY,2024,188:E546-E554.
APA	Liu, Jiali.,Chen, Shouxuan.,Chen, Jianwei.,Wang, Bo.,Zhang, Qiusheng.,...&Zhang, Doudou.(2024).Structural Brain Connectivity Guided Optimal Contact Selection for Deep Brain Stimulation of the Subthalamic Nucleus.WORLD NEUROSURGERY,188,E546-E554.
MLA	Liu, Jiali,et al."Structural Brain Connectivity Guided Optimal Contact Selection for Deep Brain Stimulation of the Subthalamic Nucleus".WORLD NEUROSURGERY 188(2024):E546-E554.