Direct and indirect effects of error monitoring on social functioning in a cohort with high-risk and first-episode psychosis

doi:10.1016/j.pnpbp.2023.110904

	Direct and indirect effects of error monitoring on social functioning in a cohort with high-risk and first-episode psychosis
	Xu, Lihua 1; Hong, Xiangfei 1; Tang, Yingying 1; Cui, Huiru 1; Wei, Yanyan 1; Qian, Zhenying 1; Su, Wenjun 1; Tang, Xiaochen 1; Hu, Yegang 1; Zhang, Dan 1; Zheng, Wensi 1; Wang, Yingchan 2; Hu, Hao 3; Zhu, Junjuan 1; Zhang, Tianhong 1,4; Wang, Jijun 1,5,6
	2024-02-08
发表期刊	PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
ISSN	0278-5846
卷号	129 页码:9
摘要	Error monitoring plays a key role in people's adjustment to social life. This study aimed to examine the direct (DE) and indirect effects (IDE) of error monitoring, as indicated by error-related negativity (ERN), on social functioning in a clinical cohort from high-risk (APS) to first-episode psychosis (FEP). This study recruited 100 outpatients and 49 healthy controls (HC). ERN was recorded during a modified flanker task; social functioning was evaluated using the social scale of global functioning. The path analysis was executed using the "lavaan" package. When controlling for age and education, the clinical cohort had a smaller ERN than the HC group (F1, 145 = 19.58, p < 0.001, partial eta 2 = 0.12, 95%CI: 0.04-0.22). ERN demonstrated no substantial direct impact on current social functioning; however, it manifested indirect influences on social functioning via the disorganization factor of the Positive and Negative Syndrome Scale, both with (standardized IDE: -0.139, p = 0.009) and without (standardized IDE: -0.087, p = 0.018) accounting for the diagnosis, defined as a dummy variable (FEP =1 and APS = 0) and included as a covariate. These findings suggest that error monitoring, as indicated by ERN, may serve as a potential prognostic indicator of social functioning in patients with psychosis.
关键词	Disorganization Event-related negativity First-episode psychosis High-risk psychosis Social functioning
DOI	10.1016/j.pnpbp.2023.110904
收录类别	SCI
语种	英语
资助项目	Shanghai Mental Health Center[CRC2018ZD01] ; Shanghai Mental Health Center[CRC2018YB01] ; Shanghai Mental Health Center[CRC2019ZD02] ; [2019-zd01] ; [2020-FX-02] ; [2020-FX-05]
WOS研究方向	Neurosciences & Neurology ; Pharmacology & Pharmacy ; Psychiatry
WOS类目	Clinical Neurology ; Neurosciences ; Pharmacology & Pharmacy ; Psychiatry
WOS记录号	WOS:001134001900001
出版者	PERGAMON-ELSEVIER SCIENCE LTD
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/38476
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Hong, Xiangfei; Zhang, Tianhong; Wang, Jijun
作者单位	1.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Shanghai Key Lab Psychot Disorders, Shanghai 200030, Peoples R China 2.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Dept Psychiat, Sch Med, Shanghai 200030, Peoples R China 3.Shanghai Jiao Tong Univ Sch Med, Shanghai Mental Hlth Ctr, Dept Early Psychot Disorders, Dept Early Psychot Disorders, Shanghai 200030, Peoples R China 4.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Imaging Ctr, Shanghai 200030, Peoples R China 5.Univ Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, SKL Comp Architecture, Inst Comp Technol,CAS,CEBSIT, Beijing, Peoples R China 6.Shanghai Jiao Tong Univ, Inst Psychol & Behav Sci, Shanghai, Peoples R China
推荐引用方式 GB/T 7714	Xu, Lihua,Hong, Xiangfei,Tang, Yingying,et al. Direct and indirect effects of error monitoring on social functioning in a cohort with high-risk and first-episode psychosis[J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,2024,129:9.
APA	Xu, Lihua.,Hong, Xiangfei.,Tang, Yingying.,Cui, Huiru.,Wei, Yanyan.,...&Wang, Jijun.(2024).Direct and indirect effects of error monitoring on social functioning in a cohort with high-risk and first-episode psychosis.PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,129,9.
MLA	Xu, Lihua,et al."Direct and indirect effects of error monitoring on social functioning in a cohort with high-risk and first-episode psychosis".PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 129(2024):9.