MarkerDetector: A method for robust fiducial marker detection in electron micrographs using wavelet-based template

doi:10.1016/j.jsb.2023.108044

	MarkerDetector: A method for robust fiducial marker detection in electron micrographs using wavelet-based template
	Hou, Gaoxin 1; Yang, Zhidong 2,3; Zang, Dawei 2; Fernandez, Jose-Jesus 4; Zhang, Fa 5; Han, Renmin 1,6
	2024-03-01
发表期刊	JOURNAL OF STRUCTURAL BIOLOGY
ISSN	1047-8477
卷号	216 期号:1 页码:13
摘要	Fiducial marker detection in electron micrographs becomes an important and challenging task with the development of large-field electron microscopy. The fiducial marker detection plays an important role in several steps during the process of electron micrographs, such as the alignment and parameter calibrations. However, limited by the conditions of low signal-to-noise ratio (SNR) in the electron micrographs, the performance of fiducial marker detection is severely affected. In this work, we propose the MarkerDetector, a novel algorithm for detecting fiducial markers in electron micrographs. The proposed MarkerDetector is built upon the following contributions: Firstly, a wavelet-based template generation algorithm is devised in MarkerDetector. By adopting a shape-based criterion, a high-quality template can be obtained. Secondly, a robust marker determination strategy is devised by utilizing statistic-based filtering, which can guarantee the correctness of the detected fiducial markers. The average running time of our algorithm is 1.67 seconds with promising accuracy, indicating its practical feasibility for applications in electron micrographs.
关键词	Electron microscopy Wavelet transform Template matching Fiducial marker detection
DOI	10.1016/j.jsb.2023.108044
收录类别	SCI
语种	英语
资助项目	Natural Science Foundation of Shandong Province[62072441] ; Natural Science Foundation of Shandong Province[32241027] ; King Abdullah University of Science and Technology (KAUST) Office of Research Administration (ORA)[ZR2023YQ057] ; Youth Innovation Promotion Association CAS[URF/1/4352-01-01] ; Youth Innovation Promotion Association CAS[REI/1/5234-01-01] ; Youth Innovation Promotion Association CAS[REI/1/5414-01-01] ; Young Scientists Fund of the National Natural Science Foundation of China[61902373] ; Foundation of the Chinese Academy of Sciences, China ; Strategic Priority Research Program of the Chinese Academy of Sciences, China[XDB24050300] ; Strategic Priority Research Program of the Chinese Academy of Sciences, China[XDB44030300] ; Shanghai Municipal Science and Technology Major Project ; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence (LCNBI)[2018SHZDZX01] ; Instrument Improvement Funds of Shandong University Public Technology Platform
WOS研究方向	Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
WOS类目	Biochemistry & Molecular Biology ; Biophysics ; Cell Biology
WOS记录号	WOS:001140177000001
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/38424
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Zhang, Fa; Han, Renmin
作者单位	1.Shandong Univ, Res Ctr Math & Interdisciplinary Sci, Frontiers Sci Ctr Nonlinear Expectat, Minist Educ, Qingdao 266237, Peoples R China 2.Chinese Acad Sci, Inst Comp Technol, High Performance Comp Res Ctr, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Spanish Natl Res Council CINN CSIC, Hlth Res Inst Asturias ISPA, Av Hosp Univ S-N, Oviedo 33011, Spain 5.Beijing Inst Technol, Sch Med Technol, Beijing 100081, Peoples R China 6.King Abdullah Univ Sci & Technol KAUST, Computat Biosci Res Ctr CBRC, Comp Elect & Math Sci & Engn CEMSE Div, Thuwal 23955, Saudi Arabia
推荐引用方式 GB/T 7714	Hou, Gaoxin,Yang, Zhidong,Zang, Dawei,et al. MarkerDetector: A method for robust fiducial marker detection in electron micrographs using wavelet-based template[J]. JOURNAL OF STRUCTURAL BIOLOGY,2024,216(1):13.
APA	Hou, Gaoxin,Yang, Zhidong,Zang, Dawei,Fernandez, Jose-Jesus,Zhang, Fa,&Han, Renmin.(2024).MarkerDetector: A method for robust fiducial marker detection in electron micrographs using wavelet-based template.JOURNAL OF STRUCTURAL BIOLOGY,216(1),13.
MLA	Hou, Gaoxin,et al."MarkerDetector: A method for robust fiducial marker detection in electron micrographs using wavelet-based template".JOURNAL OF STRUCTURAL BIOLOGY 216.1(2024):13.