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NPInter v4.0: an integrated database of ncRNA interactions
Teng, Xueyi1,2; Chen, Xiaomin1,2; Xue, Hua1,2; Tang, Yiheng1,2; Zhang, Peng1; Kang, Quan1; Hao, Yajing1,2; Chen, Runsheng1,2,3; Zhao, Yi4; He, Shunmin1,2
2020-01-08
发表期刊NUCLEIC ACIDS RESEARCH
ISSN0305-1048
卷号48期号:D1页码:D160-D165
摘要Noncoding RNAs (ncRNAs) play crucial regulatory roles in a variety of biological circuits. To document regulatory interactions between ncRNAs and biomolecules, we previously created the NPInter database (http://bigdata.ibp.ac.cn/npinter). Since the last version of NPInter was issued, a rapidly growing number of studies have reported novel interactions and accumulated numerous high-throughput interactome data. We have therefore updated NPInter to its fourth edition in which are integrated 600 000 new experimentally identified ncRNA interactions. ncRNA-DNA interactions derived from ChIRP-seq data and circular RNA interactions have been included in the database. Additionally, disease associations were annotated to the interactingmolecules. The database website has also been redesigned with a more user-friendly interface and several additional functional modules. Overall, NPInter v4.0 now provides more comprehensive data and services for researchers working on ncRNAs and their interactions with other biomolecules.
DOI10.1093/nar/gkz969
收录类别SCI
语种英语
资助项目National Natural Science Foundation of China[31701117] ; National Natural Science Foundation of China[31970647] ; National Key R&D Program of China[2016YFC0901702] ; National Key R&D Program of China[2017YFC0907503] ; 13th Five-Year Informatization Plan of Chinese Academy of Sciences[XXH13505-05]
WOS研究方向Biochemistry & Molecular Biology
WOS类目Biochemistry & Molecular Biology
WOS记录号WOS:000525956700024
出版者OXFORD UNIV PRESS
引用统计
被引频次:126[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://119.78.100.204/handle/2XEOYT63/14246
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Chen, Runsheng; Zhao, Yi; He, Shunmin
作者单位1.Chinese Acad Sci, Ctr Big Data Res Hlth, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Guangdong Geneway Decoding Biotech Co Ltd, Foshan 528316, Peoples R China
4.Chinese Acad Sci, Adv Comp Res Ctr, Inst Comp Technol, Key Lab Intelligent Informat Proc,Bioinformat Res, Beijing 100190, Peoples R China
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GB/T 7714
Teng, Xueyi,Chen, Xiaomin,Xue, Hua,et al. NPInter v4.0: an integrated database of ncRNA interactions[J]. NUCLEIC ACIDS RESEARCH,2020,48(D1):D160-D165.
APA Teng, Xueyi.,Chen, Xiaomin.,Xue, Hua.,Tang, Yiheng.,Zhang, Peng.,...&He, Shunmin.(2020).NPInter v4.0: an integrated database of ncRNA interactions.NUCLEIC ACIDS RESEARCH,48(D1),D160-D165.
MLA Teng, Xueyi,et al."NPInter v4.0: an integrated database of ncRNA interactions".NUCLEIC ACIDS RESEARCH 48.D1(2020):D160-D165.
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