ncFANs: a web server for functional annotation of long non-coding RNAs

doi:10.1093/nar/gkr432

	ncFANs: a web server for functional annotation of long non-coding RNAs
	Liao, Qi 1,2,3; Xiao, Hui 1; Bu, Dechao 1,4; Xie, Chaoyong 1; Miao, Ruoyu 5,6; Luo, Haitao 1; Zhao, Guoguang 1,4; Yu, Kuntao 1,4; Zhao, Haitao 5,6; Skogerbo, Geir 7,8; Chen, Runsheng 7,8; Wu, Zhongdao 2,3; Liu, Changning 1; Zhao, Yi 1
	2011-07-01
发表期刊	NUCLEIC ACIDS RESEARCH
ISSN	0305-1048
卷号	39 页码:W118-W124
摘要	Recent interest in the non-coding transcriptome has resulted in the identification of large numbers of long non-coding RNAs (lncRNAs) in mammalian genomes, most of which have not been functionally characterized. Computational exploration of the potential functions of these lncRNAs will therefore facilitate further work in this field of research. We have developed a practical and user-friendly web interface called ncFANs (non-coding RNA Function ANnotation server), which is the first web service for functional annotation of human and mouse lncRNAs. On the basis of the re-annotated Affymetrix microarray data, ncFANs provides two alternative strategies for lncRNA functional annotation: one utilizing three aspects of a coding-non-coding gene co-expression (CNC) network, the other identifying condition-related differentially expressed lncRNAs. ncFANs introduces a highly efficient way of re-using the abundant pre-existing microarray data. The present version of ncFANs includes re-annotated CDF files for 10 human and mouse Affymetrix microarrays, and the server will be continuously updated with more re-annotated microarray platforms and lncRNA data. ncFANs is freely accessible at http://www.ebiomed.org/ncFANs/ or http://www.noncode.org/ncFANs/.
DOI	10.1093/nar/gkr432
收录类别	SCI
语种	英语
资助项目	Chinese Academy of Sciences[KSCX2-EW-R-01] ; Beijing Institutes of Life Science ; National Natural Science Foundation of China[31071137] ; National Natural Science Foundation of China[31000586] ; National Natural Science Foundation of China[30970623] ; International Science and Technology Cooperation Projects[2010DFA31840] ; International Science and Technology Cooperation Projects[2010DFB33720]
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
WOS记录号	WOS:000292325300020
出版者	OXFORD UNIV PRESS
引用统计	被引频次：104[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.204/handle/2XEOYT63/12598
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Zhao, Yi
作者单位	1.Chinese Acad Sci, Bioinformat Res Grp, Key Lab Intelligent Informat Proc, Adv Comp Res Lab,Inst Comp Technol, Beijing, Peoples R China 2.Sun Yat Sen Univ, Dept Parasitol, Zhongshan Sch Med, Guangzhou 510275, Guangdong, Peoples R China 3.Sun Yat Sen Univ, Key Lab Trop Dis Control, Minist Educ, Guangzhou 510275, Guangdong, Peoples R China 4.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 5.Chinese Acad Med Sci, Dept Liver Surg, Peking Union Med Coll Hosp, Beijing 100730, Peoples R China 6.PUMC, Beijing 100730, Peoples R China 7.Chinese Acad Sci, Inst Biophys, Bioinformat Lab, Beijing 100080, Peoples R China 8.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Liao, Qi,Xiao, Hui,Bu, Dechao,et al. ncFANs: a web server for functional annotation of long non-coding RNAs[J]. NUCLEIC ACIDS RESEARCH,2011,39:W118-W124.
APA	Liao, Qi.,Xiao, Hui.,Bu, Dechao.,Xie, Chaoyong.,Miao, Ruoyu.,...&Zhao, Yi.(2011).ncFANs: a web server for functional annotation of long non-coding RNAs.NUCLEIC ACIDS RESEARCH,39,W118-W124.
MLA	Liao, Qi,et al."ncFANs: a web server for functional annotation of long non-coding RNAs".NUCLEIC ACIDS RESEARCH 39(2011):W118-W124.