Institute of Computing Technology, Chinese Academy IR
| ZOOM! Zillions of oligos mapped | |
| Lin, Hao2; Zhang, Zefeng2; Zhang, Michael Q.3; Ma, Bin1; Li, Ming4 | |
| 2008-11-01 | |
| 发表期刊 | BIOINFORMATICS
 |
| ISSN | 1367-4803 |
| 卷号 | 24期号:21页码:2431-2437 |
| 摘要 | Motivation: The next generation sequencing technologies are generating billions of short reads daily. Resequencing and personalized medicine need much faster software to map these deep sequencing reads to a reference genome, to identify SNPs or rare transcripts. Results: We present a framework for how full sensitivity mapping can be done in the most efficient way, via spaced seeds. Using the framework, we have developed software called ZOOM, which is able to map the Illumina/Solexa reads of 15x coverage of a human genome to the reference human genome in one CPU-day, allowing two mismatches, at full sensitivity. |
| DOI | 10.1093/bioinformatics/btn416 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | NSF China[60496320] ; NSF China[30500104] ; NSF China[30570393] ; NSF China[0324292] ; National Institutes of Health[HG001696] ; NSERC and Canada Research Chair program ; NSERC[RGPIN46506] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics |
| WOS类目 | Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability |
| WOS记录号 | WOS:000260381200003 |
| 出版者 | OXFORD UNIV PRESS |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.204/handle/2XEOYT63/11174 |
| 专题 | 中国科学院计算技术研究所期刊论文_英文 |
| 通讯作者 | Ma, Bin |
| 作者单位 | 1.Univ Western Ontario, Dept Comp Sci, London, ON N6A 5B8, Canada 2.Chinese Acad Sci, Comp Technol Inst, Beijing, Peoples R China 3.Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA 4.Univ Waterloo, David R Cheriton Sch Comp Sci, Waterloo, ON N2L 3G1, Canada |
| 推荐引用方式 GB/T 7714 | Lin, Hao,Zhang, Zefeng,Zhang, Michael Q.,et al. ZOOM! Zillions of oligos mapped[J]. BIOINFORMATICS,2008,24(21):2431-2437. |
| APA | Lin, Hao,Zhang, Zefeng,Zhang, Michael Q.,Ma, Bin,&Li, Ming.(2008).ZOOM! Zillions of oligos mapped.BIOINFORMATICS,24(21),2431-2437. |
| MLA | Lin, Hao,et al."ZOOM! Zillions of oligos mapped".BIOINFORMATICS 24.21(2008):2431-2437. |
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论