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NONCODE: an integrated knowledge database of non-coding RNAs
Liu, CN; Bai, BY; Skogerbo, G; Cai, L; Deng, W; Zhang, Y; Bu, DB; Zhao, Y; Chen, RS
2005
发表期刊NUCLEIC ACIDS RESEARCH
ISSN0305-1048
卷号33页码:D112-D115
摘要NONCODE is an integrated knowledge database dedicated to non-coding RNAs (ncRNAs), that is to say, RNAs that function without being translated into proteins. All ncRNAs in NONCODE were filtered automatically from literature and GenBank, and were later manually curated. The distinctive features of NONCODE are as follows: (i) the ncRNAs in NONCODE include almost all the types of ncRNAs, except transfer RNAs and ribosomal RNAs. (ii) All ncRNA sequences and their related information (e.g. function, cellular role, cellular location, chromosomal information, etc.) in NONCODE have been confirmed manually by consulting relevant literature: more than 80% of the entries are based on experimental data. (iii) Based on the cellular process and function, which a given ncRNA is involved in,we introduced a novel classification system, labeled process function class, to integrate existing classification systems. (iv) In addition, some 1100 ncRNAs have been grouped into nine other classes according to whether they are specific to gender or tissue or associated with tumors and diseases, etc. (v) NONCODE provides a user-friendly interface, a visualization platform and a convenient search option, allowing efficient recovery of sequence, regulatory elements in the flanking sequences, secondary structure, related publications and other information. The first release of NONCODE (v1.0) contains 5339 non-redundant sequences from 861 organisms, including eukaryotes, eubacteria, archaebacteria, virus and viroids. Access is free for all users through a web interface at http://noncode.bioinfo.org.cn.
DOI10.1093/nar/gki041
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology
WOS类目Biochemistry & Molecular Biology
WOS记录号WOS:000226524300020
出版者OXFORD UNIV PRESS
引用统计
被引频次:239[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://119.78.100.204/handle/2XEOYT63/10115
专题中国科学院计算技术研究所期刊论文_英文
通讯作者Chen, RS
作者单位1.Chinese Acad Sci, Inst Biophys, Bioinformat Lab, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Comp Technol Inst, Key Lab Intelligent Informat Proc, Bioinformat Res Grp, Beijing 100080, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
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Liu, CN,Bai, BY,Skogerbo, G,et al. NONCODE: an integrated knowledge database of non-coding RNAs[J]. NUCLEIC ACIDS RESEARCH,2005,33:D112-D115.
APA Liu, CN.,Bai, BY.,Skogerbo, G.,Cai, L.,Deng, W.,...&Chen, RS.(2005).NONCODE: an integrated knowledge database of non-coding RNAs.NUCLEIC ACIDS RESEARCH,33,D112-D115.
MLA Liu, CN,et al."NONCODE: an integrated knowledge database of non-coding RNAs".NUCLEIC ACIDS RESEARCH 33(2005):D112-D115.
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